NUP88 抗体 (AA 314-425)
(3 references)-
- 抗原 See all NUP88 抗体
- NUP88 (Nucleoporin 88kDa (NUP88))
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抗原表位
- AA 314-425
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NUP88 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Nup88 aa. 314-425
- 克隆位点
- 22-Nup88
- 亚型
- IgG1
- Top Product
- Discover our top product NUP88 Primary Antibody
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anti-Nucleoporin 88kDa (NUP88) (AA 57-296) antibody
NUP88 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 88kDa (NUP88) (Internal Region) antibodyNUP88 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 88kDa (NUP88) (Internal Region) antibodyNUP88 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 88kDa (NUP88) (Internal Region) antibodyNUP88 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nucleoporin 88kDa (NUP88) (Internal Region) antibodyNUP88 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "The nuclear pore complex protein Nup88 is overexpressed in tumor cells." in: Cancer research, Vol. 59, Issue 21, pp. 5408-11, (1999) (PubMed).
: "Nup84, a novel nucleoporin that is associated with CAN/Nup214 on the cytoplasmic face of the nuclear pore complex." in: The Journal of cell biology, Vol. 137, Issue 5, pp. 989-1000, (1997) (PubMed).
: "The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88." in: The EMBO journal, Vol. 16, Issue 4, pp. 807-16, (1997) (PubMed).
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: "The nuclear pore complex protein Nup88 is overexpressed in tumor cells." in: Cancer research, Vol. 59, Issue 21, pp. 5408-11, (1999) (PubMed).
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- 抗原
- NUP88 (Nucleoporin 88kDa (NUP88))
- 别名
- Nup88 (NUP88 产品)
- 别名
- nup88B antibody, nup88 antibody, nup88A antibody, Nup84 antibody, Prei2 antibody, nucleoporin 88 antibody, nucleoporin 88kDa S homeolog antibody, nucleoporin 88kDa L homeolog antibody, nucleoporin 88kDa antibody, NUP88 antibody, nup88.S antibody, nup88.L antibody, nup88 antibody, Nup88 antibody
- 背景
- Nucleocytoplasmic transport involves the binding and interaction of several cytosolic and nuclear pore proteins by at least two different mechanisms. One mechanism is mediated by karyopherins to transport proteins with the nuclear localization sequence (NLS) and an alternative pathway uses the protein Transportin. Morphologically both pathways require the use of the nuclear pore complex (NPC) which acts as a gate mediating active transport of proteins and RNA into and out of the nucleus. The NLS binds to karyopherin alpha, and to the N-terminal region of karyopherin beta. Both karyopherins bind to repeat sequences of nucleoporins at the nuclear envelope. p62 is the best characterized member of a group of nucleoporins that line the central region of the NPC. A tightly associated complex is formed by p62 and two other nucleoporins, p54 and p58. Nup88 is a nonglycosylated nucleoporin, that does not contain the characteristic GLFG or XFXFG repeats found in other NPC proteins. The structure of Nup88 includes a coiled-coil domain required for association with the NPC. Nup88 is overexpressed during oncogenesis and development, and forms a complex with the nuclear transport factors, Exportin-1 and Nup214.
- 分子量
- 88 kDa
- 途径
- SARS-CoV-2 Protein Interactome
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