ALIX 抗体 (AA 375-580)
(2 references)-
- 抗原 See all ALIX (PDCD6IP) 抗体
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
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抗原表位
- AA 375-580
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适用
- 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ALIX antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse AIP1 aa. 375-580
- 克隆位点
- 49-AIP1
- 亚型
- IgG1
- Top Product
- Discover our top product PDCD6IP Primary Antibody
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anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-239) antibody
PDCD6IP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-180) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 174-383) antibodyPDCD6IP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-110) antibodyPDCD6IP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 601-700) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人 WB, ELISA, FACS 宿主: 兔 Monoclonal 7E9 unconjugated Recombinant Antibody
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (C-Term) antibodyPDCD6IP 适用: 人 WB 宿主: 山羊 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 19275-81, (2000) (PubMed).
: "Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction." in: The Journal of biological chemistry, Vol. 274, Issue 3, pp. 1533-40, (1999) (PubMed).
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: "The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 19275-81, (2000) (PubMed).
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- 抗原
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
- 别名
- AIP1 (PDCD6IP 产品)
- 别名
- DDBDRAFT_0167145 antibody, DDBDRAFT_0185177 antibody, DDB_0167145 antibody, DDB_0185177 antibody, AIP1 antibody, ALIX antibody, DRIP4 antibody, HP95 antibody, AI480591 antibody, AW544830 antibody, Aip1 antibody, Alix antibody, C76364 antibody, Eig2 antibody, mKIAA1375 antibody, CG12876 antibody, DAIP1 antibody, Dmel\\CG12876 antibody, GB11744 antibody, RGD1561176 antibody, zgc:63638 antibody, wu:fb70d03 antibody, wu:fy65h02 antibody, PDCD6IP antibody, aip1 antibody, alix antibody, hp95 antibody, drip4 antibody, ALG-2 interacting protein X antibody, programmed cell death 6 interacting protein antibody, programmed cell death 6-interacting protein antibody, Programmed cell death 6 interacting protein antibody, programmed cell death 6 interacting protein L homeolog antibody, alxA antibody, PDCD6IP antibody, Pdcd6ip antibody, ALiX antibody, LOC412662 antibody, pdcd6ip antibody, Bm1_48390 antibody, pdcd6ip.L antibody
- 背景
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Apoptosis is a selective process of genetically programmed cell death which occurs during normal cell differentiation and development of multicellular organisms. In vertebrates, T cell and neuronal development are probably the best characterized systems for the study of apoptosis. ALG-2 and ALG-3 (apoptosis-linked genes 2 and 3) were identified as low molecular weight Ca2+-binding proteins essential for apoptosis through the activation of the Fas receptor in T cells. ALG-2 Interacting Protein 1 (AIP1/Alix) is a ubiquitous protein that associates with ALG-2 in the cytosol in a Ca2+ dependent manner. AIP1 is homologous to the yeast protein, BRO1, which has been implicated in Pkc1p- AP kinase signaling. A truncated form of AIP1 protects against serum starvation-, etoposide-, and staurosporine-induced cell death. In addition, the C-terminal proline rich region of AIP1 facilitates interaction with SH3 domain-containing protein expressed in tumorigenic astrocytes (SETA) and this interaction may be important for mediating DNA damage-dependent apoptosis in astrocytes. Thus, AIP1 interacts with ALG-2 or SETA, or both, during activation of cell death pathways in a variety of cell types.
Synonyms: ALG-2 Interacting Protein 1, Alix - 分子量
- 105 kDa
- 途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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