TAO Kinase 2 抗体 (AA 352-550)
(1 reference)-
- 抗原 See all TAO Kinase 2 (TAOK2) 抗体
- TAO Kinase 2 (TAOK2)
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抗原表位
- AA 352-550
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TAO Kinase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 小鼠, 人
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat TAO1 aa. 352-550
- 克隆位点
- 22-TAO1
- 亚型
- IgG2a
- Top Product
- Discover our top product TAOK2 Primary Antibody
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anti-TAO Kinase 2 (TAOK2) (AA 831-930) antibody
TAOK2 适用: 人 ELISA, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 831-930) antibodyTAOK2 适用: 人 ELISA, WB, IF, PLA 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-TAO Kinase 2 (TAOK2) (pSer181) antibodyTAOK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 719-880) antibodyTAOK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (pSer181) antibodyTAOK2 适用: 人, 小鼠, 大鼠, 犬, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAO Kinase 2 (TAOK2) (AA 610-730) antibodyTAOK2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 28625-32, (1998) (PubMed).
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: "Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades." in: The Journal of biological chemistry, Vol. 273, Issue 44, pp. 28625-32, (1998) (PubMed).
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- 抗原
- TAO Kinase 2 (TAOK2)
- 别名
- TAO1 (TAOK2 产品)
- 别名
- MAP3K17 antibody, PSK antibody, PSK1 antibody, PSK1-BETA antibody, TAO1 antibody, TAO2 antibody, Tao2 antibody, 1110033K02Rik antibody, B230344N16 antibody, mKIAA0881 antibody, TAOK2 antibody, map3k17 antibody, psk antibody, psk1 antibody, tao1 antibody, tao2 antibody, TAO kinase 2 antibody, TAO kinase 2 L homeolog antibody, serine/threonine-protein kinase TAO2 antibody, TAOK2 antibody, Taok2 antibody, taok2.L antibody, taok2 antibody, LOC100085396 antibody
- 背景
- Mitogen activated protein kinases (MAPKs) are critical components of several signal transduction pathways that convert extracellular stimuli into cellular responses. Four groups of MAPKs (ERKs, JNKs, p38, and ERK5) have been identified in mammalian cells. MAPK pathways contain a 3-kinase cascade consisting of a MAPK, a MAP/ERK kinase (MEK), and a MEK kinase (MEKK). MEKK phosphorylation of MEKs leads to activation and subsequent MEK-mediated phosphorylation of both Thr and Tyr residues at the Thr-X-Tyr dual phosphorylation motif of MAPKs. TAO1 was isolated from a rat cDNA library using the sequence from yeast Ste20p kinase. Sequence analysis shows that TAO1 contains an N-terminal Ser/Thr protein kinase domain, an acidic domain, and two serine-rich domains. The catalytic domain of TAO1 is 40% identical to the p21-activated kinases, PAK1 and PAK2, and 33% identical to MEKK1. TAO1 expression is highest in brain, but it is also detected in heart and lung. TAO1 can activate MEK3, MEK4, and MEK6 from the stress-responsive MAPK pathway, but not MEK1 or 2 from the classical MAPK pathway. Thus, TAO1 may be an important MEKK in the p38-containing stress-responsive MAPK pathway.
- 分子量
- 116 kDa
- 途径
- Cell-Cell Junction Organization
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