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STX8 抗体 (AA 57-164)

STX8 适用: 人, 小鼠, 大鼠, 犬 WB, IF 宿主: 小鼠 Monoclonal 48-Syntaxin 8 unconjugated
产品编号 ABIN968489
发货至: 中国
  • 抗原 See all STX8 抗体
    STX8 (Syntaxin 8 (STX8))
    抗原表位
    • 8
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 57-164
    适用
    • 28
    • 23
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 37
    • 3
    • 1
    小鼠
    克隆类型
    • 40
    • 1
    单克隆
    标记
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STX8 antibody is un-conjugated
    应用范围
    • 29
    • 20
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 犬, 大鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse Syntaxin 8 aa. 57-164
    克隆位点
    48-Syntaxin 8
    亚型
    IgG2a
    Top Product
    Discover our top product STX8 Primary Antibody
  • 说明

    Related Products: ABIN967389, ABIN968536

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).

    Thoreau, Bergès, Callebaut, Guillier-Gencik, Gressin, Bernheim, Karst, Mornon, Kitzis, Chomel: "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)." in: Biochemical and biophysical research communications, Vol. 257, Issue 2, pp. 577-83, (1999) (PubMed).

  • 抗原
    STX8 (Syntaxin 8 (STX8))
    别名
    Syntaxin 8 (STX8 产品)
    别名
    CG4109 antibody, Dm Syx8 antibody, DmSyx8 antibody, Dmel\\CG4109 antibody, SYX8 antibody, Syx antibody, zgc:64079 antibody, syntaxin-8 antibody, STX8 antibody, GB11192 antibody, MGC116467 antibody, DDBDRAFT_0217663 antibody, DDBDRAFT_0231533 antibody, DDB_0217663 antibody, DDB_0231533 antibody, CARB antibody, 0610007H08Rik antibody, 1110002H11Rik antibody, 4930571E13Rik antibody, Syntaxin 8 antibody, syntaxin 8 antibody, syntaxin-8 antibody, syntaxin 8 S homeolog antibody, Syx8 antibody, stx8 antibody, STX8 antibody, LOC552098 antibody, stx8.S antibody, syn8A antibody, Stx8 antibody
    背景
    Eukaryotic protein trafficking involves the packaging of molecules into membranous vesicles that bud from a donor compartment, travel to a specific destination, fuse, and release their components into an acceptor compartment. Recognition between vesicle and acceptor membrane is mediated by the pairing of the integral membrane SNARE proteins. The stable interaction between vesicle proteins (v-SNAREs) and target proteins (t-SNAREs) juxtaposes the membranes and results in an activated docking state and/or membrane fusion. The syntaxin protein family contains a number of members that serve as functional t-SNAREs. One member of this family, syntaxin 8, has two coiled-coil domains, one in the N-terminus and one toward the C-terminus. The C-terminal domain is homologous to a similar domain in syntaxin 6 and is predicted to interact in the formation of SNARE complexes, while a hydrophobic domain in the C-terminus may be involved in membrane anchoring. Syntaxin-8 is ubiquitously expressed, but is present at high levels in the heart and localizes specifically to the ER. Thus, syntaxin-8 is a t-SNARE that is thought to be involved in the early secretory pathway of many different cell types.
    分子量
    27 kDa
    途径
    Synaptic Vesicle Exocytosis
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