电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NMT2 抗体 (AA 10-119)

NMT2 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 30-NMT unconjugated
产品编号 ABIN968466
发货至: 中国
  • 抗原 See all NMT2 抗体
    NMT2 (N-Myristoyltransferase 2 (NMT2))
    抗原表位
    • 15
    • 10
    • 9
    • 8
    • 8
    • 6
    • 3
    • 2
    • 1
    AA 10-119
    适用
    • 66
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 61
    • 5
    小鼠
    克隆类型
    • 62
    • 4
    单克隆
    标记
    • 26
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NMT2 antibody is un-conjugated
    应用范围
    • 53
    • 25
    • 13
    • 13
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human NMT-2 aa. 10-119
    克隆位点
    30-NMT
    亚型
    IgG1
    Top Product
    Discover our top product NMT2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Giang, Cravatt: "A second mammalian N-myristoyltransferase." in: The Journal of biological chemistry, Vol. 273, Issue 12, pp. 6595-8, (1998) (PubMed).

  • 抗原
    NMT2 (N-Myristoyltransferase 2 (NMT2))
    别名
    NMT-2 (NMT2 产品)
    别名
    NMT2 antibody, A930001K02Rik antibody, AI605445 antibody, AU044698 antibody, hNMT-2 antibody, NMT 2 antibody, fb40e03 antibody, wu:fb40e03 antibody, N-myristoyltransferase 2 antibody, NMT2 antibody, Bm1_22900 antibody, LOAG_05681 antibody, nmt2 antibody, Nmt2 antibody
    背景
    Myristoylation is an essential cotranslational modification for many mammalian, viral, and fungal signaling proteins. N-terminal myristoylation is a lipid modification that is catalyzed by N-myristoyltransferase (NMT). NMT transfers myristic acid from myristoyl coenzyme A to the amino group of a protein's N-terminal glycine residue. This modification is important for localization and/or function of many of these proteins. Two human NMTs (NMT-1, NMT-2) have been identified. These proteins share 95% amino acid identity with their mouse homologs. NMT-1 is processed to form four protein isoforms with molecular weights ranging from 49-68 kDa. It is not known if these four isoforms are derived from single or multiple gene(s) and their exact functional roles are yet to be determined. In contrast to NMT-1, NMT-2 is a single 65 kDa protein. It contains 77% sequence identity with NMT-1, indicating that these proteins comprise two distinct families with overlapping, but distinct, substrate preferences. Additionally, NMT enzymatic activity is increased in colorectal tumors. Thus, NMTs are transferases whose function is essential for biological function of a variety of signaling proteins.
    分子量
    65 kDa
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
You are here:
客服