Sorting Nexin 2 抗体 (AA 15-137)
(2 references)-
- 抗原 See all Sorting Nexin 2 (SNX2) 抗体
- Sorting Nexin 2 (SNX2)
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抗原表位
- AA 15-137
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适用
- 人, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Sorting Nexin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human SNX2 aa. 15-137
- 克隆位点
- 13-SNX2
- 亚型
- IgG1
- Top Product
- Discover our top product SNX2 Primary Antibody
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anti-Sorting Nexin 2 (SNX2) antibody
SNX2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 2 (SNX2) (AA 1-102) antibodySNX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 2 (SNX2) (AA 350-400) antibodySNX2 适用: 人, 小鼠, 犬, Cow, 马, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sorting Nexin 2 (SNX2) (AA 120-170) antibodySNX2 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968536, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).
: "Enhanced degradation of EGF receptors by a sorting nexin, SNX1." in: Science (New York, N.Y.), Vol. 272, Issue 5264, pp. 1008-10, (1996) (PubMed).
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: "Identification of a family of sorting nexin molecules and characterization of their association with receptors." in: Molecular and cellular biology, Vol. 18, Issue 12, pp. 7278-87, (1998) (PubMed).
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- 抗原
- Sorting Nexin 2 (SNX2)
- 别名
- SNX2 (SNX2 产品)
- 别名
- snx2 antibody, MGC64590 antibody, SNX2 antibody, LOC100219194 antibody, TRG-9 antibody, 0610030A03Rik antibody, zgc:123293 antibody, sorting nexin 2 S homeolog antibody, sorting nexin 2 antibody, snx2.S antibody, SNX2 antibody, BACOIKO006_25 antibody, snx2 antibody, Snx2 antibody
- 背景
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Biological processes such as transmembrane signaling and receptor mediated endocytosis revolve around the function of cell surface receptors. A network of molecular machinery directs the intracellular trafficking of receptors during their biosynthesis and mediates signaling downstream of receptors. The sorting nexins (SNX1, SNX1A, SNX2, SNX3, and SNX4) are a family of intracellular proteins that are thought to direct the sorting of receptor proteins. The SNX proteins contain a conserved 100 amino acid region termed the phox homology (PX) domain and are part of a family of hydrophilic proteins which includes S. cerevisiae proteins that function in protein sorting. SNX1, SNX2, and SNX4 associate predominantly with membranes and bind transmembrane receptors such as those for EGF, PDGF, and insulin. SNX1 directs the EGF receptor to the lysosomes for degradation. SNX2 forms homomeric complexes and heteromeric complexes with SNX1, SNX1A, and SNX4. These complexes are thought to be necessary for efficient protein sorting. Thus, SNX2 and other sorting nexins are thought to play important roles in the specificity of protein trafficking to and from the plasma membrane. This antibody is routinely tested by western blot analysis.
Synonyms: Sorting Nexin-2 - 分子量
- 72 kDa
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