BCAT1 抗体 (AA 213-335)
(4 references)-
- 抗原 See all BCAT1 抗体
- BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
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抗原表位
- AA 213-335
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BCAT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human ECA39 aa. 213-335
- 克隆位点
- 51-ECA39
- 亚型
- IgG1
- Top Product
- Discover our top product BCAT1 Primary Antibody
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anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 179-411) antibody
BCAT1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 158-386) antibodyBCAT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 174-386) antibodyBCAT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 321-386) antibodyBCAT1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 4-276) antibodyBCAT1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 1-320) antibodyBCAT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) antibodyBCAT1 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (C-Term) antibodyBCAT1 适用: 人, 小鼠, 大鼠, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (Internal Region) antibodyBCAT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1) (AA 1-320) antibodyBCAT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389, ABIN968535
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Involvement of Myc targets in c-myc and N-myc induced human tumors." in: Oncogene, Vol. 17, Issue 2, pp. 165-71, (1998) (PubMed).
: "ECA39 is regulated by c-Myc in human and by a Jun/Fos homolog, Gcn4, in yeast." in: Oncogene, Vol. 13, Issue 9, pp. 1859-66, (1997) (PubMed).
: "Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases." in: The Journal of biological chemistry, Vol. 271, Issue 34, pp. 20242-5, (1996) (PubMed).
: "ECA39, a conserved gene regulated by c-Myc in mice, is involved in G1/S cell cycle regulation in yeast." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 14, pp. 7143-8, (1996) (PubMed).
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: "Involvement of Myc targets in c-myc and N-myc induced human tumors." in: Oncogene, Vol. 17, Issue 2, pp. 165-71, (1998) (PubMed).
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- 抗原
- BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))
- 别名
- ECA39 (BCAT1 产品)
- 别名
- fj66g02 antibody, zgc:73157 antibody, wu:fj66g02 antibody, Bcatc antibody, BCATC antibody, BCT1 antibody, ECA39 antibody, MECA39 antibody, PNAS121 antibody, PP18 antibody, BCATc antibody, Eca39 antibody, branched chain amino-acid transaminase 1, cytosolic antibody, branched chain amino acid transaminase 1 antibody, branched chain amino-acid transaminase 1, cytosolic L homeolog antibody, branched chain aminotransferase 1, cytosolic antibody, bcat1 antibody, BCAT1 antibody, bcat1.L antibody, Bcat1 antibody
- 背景
- The c-myc oncogene is important in proliferation, differentiation, apoptosis, and malignant transformation. Products of myc oncogenes are transcription factors that bind to the DNA sequence, CACGTG, and regulate the expression of multiple target genes. Several myc target genes include ECA39, p53, ornithine decarboxylase (ODC), alpha-prothymosin, and Cdc25A. There is a high degree of identity among the mouse, human, and yeast ECA39 proteins. The myc recognition binding site of ECA39 is located 3' to the start site of transcription in the mouse and human genes, but this element is absent in the nematode and yeast. Additionally, the tissue specific expression of ECA39 during embryogenesis is similar between human and mouse. Disruption of the ECA39 gene in yeast results in an increased growth rate in comparison to wild type, such that G1 is shorter. Furthermore, ECA39 is expressed in c-myc induced tumors and displays significant homology to the prokaryotic branched-chain amino acid aminotransferase (BCAT). Thus, ECA39 may be involved in the regulation of the cell cycle, possibly at the G1 to S phase transition.
- 分子量
- 43 kDa
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