VTI1A 抗体 (AA 114-217)
(5 references)-
- 抗原 See all VTI1A 抗体
- VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))
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抗原表位
- AA 114-217
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This VTI1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠, 人, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse Vti1a aa.114-217
- 克隆位点
- 45-Vti1a
- 亚型
- IgG1
- Top Product
- Discover our top product VTI1A Primary Antibody
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anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (AA 1-175) antibody
VTI1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (AA 2-185) antibodyVTI1A 适用: 小鼠, 大鼠 WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (AA 140-169), (C-Term) antibodyVTI1A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22510 unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) antibodyVTI1A 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (Internal Region) antibodyVTI1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (N-Term) antibodyVTI1A 适用: 人, 小鼠, 犬, Cow, 马, Pig, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A) (AA 1-180) antibodyVTI1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389, ABIN968545
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis." in: The Journal of cell biology, Vol. 159, Issue 4, pp. 637-48, (2002) (PubMed).
: "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform." in: The Journal of cell biology, Vol. 156, Issue 4, pp. 653-64, (2002) (PubMed).
: "Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115." in: The Journal of cell biology, Vol. 157, Issue 1, pp. 45-62, (2002) (PubMed).
: "Seven novel mammalian SNARE proteins localize to distinct membrane compartments." in: The Journal of biological chemistry, Vol. 273, Issue 17, pp. 10317-24, (1998) (PubMed).
: "A 29-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (Vti1-rp2) implicated in protein trafficking in the secretory pathway." in: The Journal of biological chemistry, Vol. 273, Issue 34, pp. 21783-9, (1998) (PubMed).
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: "A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis." in: The Journal of cell biology, Vol. 159, Issue 4, pp. 637-48, (2002) (PubMed).
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- 抗原
- VTI1A (Vesicle Transport through Interaction with t-SNAREs 1A (VTI1A))
- 别名
- Vti1a (VTI1A 产品)
- 别名
- zgc:109895 antibody, mvti1 antibody, vti1-rp2 antibody, DDBDRAFT_0219803 antibody, DDBDRAFT_0231536 antibody, DDB_0219803 antibody, DDB_0231536 antibody, MMDS3 antibody, MVti1 antibody, VTI1RP2 antibody, Vti1-rp2 antibody, 1110014F16Rik antibody, 1110018K19Rik antibody, 4921537J05Rik antibody, MVti1a antibody, Vti1 antibody, vesicle transport through interaction with t-SNAREs 1A L homeolog antibody, vesicle transport through interaction with t-SNAREs 1A antibody, v-SNARE family protein antibody, vti1a.L antibody, vti1a antibody, VTI1A antibody, vti1A antibody, Vti1a antibody
- 背景
- Eukaryotic protein trafficking involves the packaging of molecules into membranous vesicles that bud from a donor compartment, travel to a specific destination, fuse, and release their components into an acceptor compartment. Recognition between vesicle and acceptor membrane is mediated by the pairing of the integral membrane SNARE proteins. The stable interaction between vesicle proteins (v-SNAREs) and target proteins (t-SNAREs) juxtaposes the membranes and results in an activated docked state and/or membrane fusion. VTI1a and VTI1b are putative mammalian SNARE proteins identified by sequence comparison with yeast SNAREs. In line with their involvement in vesicle transport, these molecules are expressed in a wide range of mammalian tissues. Vti1a, a possible t-SNARE, contains a C-terminal hydrophobic domain and several regions that may form coiled-coil structures. It exists in distinct syntaxin 5- and syntaxin 6-containing SNARE complexes within the Golgi apparatus. Inhibition of Vti1a blocks transport of G proteins to the cell surface and results in their accumulation within the Golgi. Thus, Vti1a functions in protein transport within the secretory pathway.
- 分子量
- 29 kDa
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