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CSRP2 抗体 (AA 601-722)

CSRP2 适用: 人, 小鼠, 大鼠, 犬 WB, IF 宿主: 小鼠 Monoclonal 8-DLP1 unconjugated
产品编号 ABIN968372
发货至: 中国
  • 抗原 See all CSRP2 抗体
    CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))
    抗原表位
    • 15
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    AA 601-722
    适用
    • 54
    • 23
    • 22
    • 17
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 63
    • 3
    • 2
    • 1
    小鼠
    克隆类型
    • 69
    单克隆
    标记
    • 21
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CSRP2 antibody is un-conjugated
    应用范围
    • 44
    • 28
    • 26
    • 26
    • 16
    • 7
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    小鼠, 人, 犬
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Please refer to us for technical protocols.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat DLP1 aa. 601-722
    克隆位点
    8-DLP1
    亚型
    IgG1
    Top Product
    Discover our top product CSRP2 Primary Antibody
  • 说明

    Related Products: ABIN967389, ABIN968545

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Bossy, Petrilli, Klinglmayr, Chen, Lütz-Meindl, Knott, Masliah, Schwarzenbacher, Bossy-Wetzel: "S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 20 Suppl 2, Issue 6, pp. S513-26, (2010) (PubMed).

    Estaquier, Arnoult: "Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis." in: Cell death and differentiation, Vol. 14, Issue 6, pp. 1086-94, (2007) (PubMed).

    Karbowski, Neutzner, Youle: "The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division." in: The Journal of cell biology, Vol. 178, Issue 1, pp. 71-84, (2007) (PubMed).

    Duvezin-Caubet, Jagasia, Wagener, Hofmann, Trifunovic, Hansson, Chomyn, Bauer, Attardi, Larsson, Neupert, Reichert: "Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology." in: The Journal of biological chemistry, Vol. 281, Issue 49, pp. 37972-9, (2006) (PubMed).

    Jofuku, Ishihara, Mihara: "Analysis of functional domains of rat mitochondrial Fis1, the mitochondrial fission-stimulating protein." in: Biochemical and biophysical research communications, Vol. 333, Issue 2, pp. 650-9, (2005) (PubMed).

    Yoon, Pitts, Dahan, McNiven: "A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells." in: The Journal of cell biology, Vol. 140, Issue 4, pp. 779-93, (1998) (PubMed).

  • 抗原
    CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))
    别名
    DLP1 (CSRP2 产品)
    别名
    CRP2 antibody, LMO5 antibody, SmLIM antibody, crp2 antibody, lmo5 antibody, csrp1 antibody, smlim antibody, AW551867 antibody, Crp2 antibody, SmLim antibody, zgc:77740 antibody, BETA-CRP antibody, csrp2 antibody, MGC81964 antibody, CSRP2 antibody, cysteine and glycine rich protein 2 antibody, cysteine and glycine-rich protein 2 antibody, cysteine and glycine rich protein 2 L homeolog antibody, cysteine and glycine rich protein 2 S homeolog antibody, CSRP2 antibody, csrp2 antibody, Csrp2 antibody, csrp2.L antibody, csrp2.S antibody
    背景
    Dynamins, phosphoproteins with intrinsic GTPase activities, play an important role during early endocytosis. The GTPase activity is stimulated in vitro by microtubules, SH3 domain containing-proteins, and Protein Kinase (PKC)- mediated phosphorylation. Although highly related, dynamins are differentially expressed in an organism. For instance, dynamin I is found only in the nervous system, dynamin II is ubiquitously expressed, and dynamin III is located in lung, testis and brain. Due to four alternative splicing products for each of the dynamins, the dynamin family contains at least 12 different members. The Dynamin Like Protein-1 (DLP1) is a new member of the dynamin family of proteins. DLP1 (also known as DVLP) is widely expressed as two alternatively spliced products, each with different tissue expression patterns. The larger product is about 84 kDa and reportedly found only in the brain, whereas the 79 kDa product is ubiquitously expressed. Unlike dynamins I-III which co-localize with endocytotic vesicles, DLP1 is found aligned with microtubules and with the endoplasmic reticulum, suggesting a secretory function for this novel protein.
    Synonyms: Dynamin Like Protein-1, DVLP
    分子量
    79-84 kDa
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