CDH15 抗体 (AA 253-366)
(5 references)-
- 抗原 See all CDH15 抗体
- CDH15 (M-Cadherin (CDH15))
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抗原表位
- AA 253-366
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适用
- 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CDH15 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse M-Cadherin aa. 253-366
- 克隆位点
- 5-M
- 亚型
- IgG2a
- Top Product
- Discover our top product CDH15 Primary Antibody
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anti-M-Cadherin (CDH15) (N-Term) antibody
CDH15 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-M-Cadherin (CDH15) (AA 355-450) antibodyCDH15 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-M-Cadherin (CDH15) (AA 639-766) antibodyCDH15 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-M-Cadherin (CDH15) (N-Term) antibodyCDH15 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-M-Cadherin (CDH15) (N-Term) antibodyCDH15 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-M-Cadherin (CDH15) (C-Term) antibodyCDH15 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 7, pp. 3989-94, (2003) (PubMed).
: "The M-cadherin catenin complex interacts with microtubules in skeletal muscle cells: implications for the fusion of myoblasts." in: Journal of cell science, Vol. 112 ( Pt 1), pp. 55-68, (1999) (PubMed).
: "Molecular cloning and characterization of a novel human classic cadherin homologous with mouse muscle cadherin." in: The Journal of biological chemistry, Vol. 273, Issue 16, pp. 10011-8, (1998) (PubMed).
: "M-cadherin-mediated cell adhesion and complex formation with the catenins in myogenic mouse cells." in: Experimental cell research, Vol. 232, Issue 2, pp. 331-8, (1997) (PubMed).
: "Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 18, pp. 8024-8, (1991) (PubMed).
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: "Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 7, pp. 3989-94, (2003) (PubMed).
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- 抗原
- CDH15 (M-Cadherin (CDH15))
- 别名
- M-Cadherin (CDH15 产品)
- 别名
- AI323380 antibody, Cdh14 antibody, Mcad antibody, CDH14 antibody, CDH3 antibody, CDHM antibody, MCAD antibody, MRD3 antibody, cadherin 15 antibody, Cdh15 antibody, CDH15 antibody
- 背景
- Cadherins are a family of transmembrane glycoproteins involved in the Ca2+-dependent cell-cell adhesion that occurs in many tissues. Members of this family include P-Cadherin, E-Cadherin (uvomorulin), N-Cadherin, R-Cadherin, Cadherin-5, L-CAM, and EP-Cadherin. These proteins are similar in their domain structure (45-74% amino acid conservation), Ca2+ and protease sensitivity, and molecular weight. However, cadherins have distinct tissue expression patterns and immunological reactivities. M (muscle)-Cadherin, another member of the Cadherin family, was discovered in myogenic mouse cells where it is present at low levels in myoblasts. It is expressed in prenatal and adult skeletal muscle and plays a role in skeletal muscle cell differentiation, particularly the fusion of myoblasts into myotubes. It is upregulated upon induction of myotube formation. M-Cadherin also forms complexes with the catenins in skeletal muscle cells, which then interact with the cytoskeleton. Therefore, it is thought that the M-Cadherin-cytoskeleton interaction may play a role in aligning myoblasts during fusion. This antibody is routinely tested by western blot analysis.
- 分子量
- 130 kDa
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