RAD23B 抗体 (AA 73-193)
(5 references)-
- 抗原 See all RAD23B 抗体
- RAD23B (RAD23 Homolog B (RAD23B))
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抗原表位
- AA 73-193
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适用
- 人, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RAD23B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human hHR23B aa. 73-193
- 克隆位点
- 16-hHR23B
- 亚型
- IgG1
- Top Product
- Discover our top product RAD23B Primary Antibody
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anti-RAD23 Homolog B (RAD23B) (AA 1-409) antibody
RAD23B 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 50-150) antibodyRAD23B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 311-409) antibodyRAD23B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-RAD23 Homolog B (RAD23B) antibodyRAD23B 适用: 人, 小鼠 WB, IHC, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 1-409) antibodyRAD23B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 164-409) antibodyRAD23B 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (Center) antibodyRAD23B 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 163-176) antibodyRAD23B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (AA 24-120) antibodyRAD23B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), ICC, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAD23 Homolog B (RAD23B) (N-Term) antibodyRAD23B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968533, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
: "Assembly, subunit composition, and footprint of human DNA repair excision nuclease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 12, pp. 6669-74, (1998) (PubMed).
: "Overproduction, purification, and characterization of the XPC subunit of the human DNA repair excision nuclease." in: The Journal of biological chemistry, Vol. 271, Issue 32, pp. 19451-6, (1996) (PubMed).
: "HHR23B, a human Rad23 homolog, stimulates XPC protein in nucleotide excision repair in vitro." in: Molecular and cellular biology, Vol. 16, Issue 9, pp. 4852-61, (1996) (PubMed).
: "Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23." in: The EMBO journal, Vol. 13, Issue 8, pp. 1831-43, (1994) (PubMed).
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: "Perturbation of SUMOlation enzyme Ubc9 by distinct domain within nucleoporin RanBP2/Nup358." in: The Journal of biological chemistry, Vol. 277, Issue 7, pp. 4755-63, (2002) (PubMed).
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- 抗原
- RAD23B (RAD23 Homolog B (RAD23B))
- 别名
- hHR23B (RAD23B 产品)
- 别名
- HHR23B antibody, HR23B antibody, P58 antibody, 0610007D13Rik antibody, AV001138 antibody, mHR23B antibody, p58 antibody, MGC107846 antibody, zgc:65951 antibody, RAD23 homolog B, nucleotide excision repair protein antibody, UV excision repair protein RAD23 homolog B antibody, RAD23 homolog B, nucleotide excision repair protein S homeolog antibody, RAD23B antibody, Rad23b antibody, rd23b antibody, rad23b antibody, rad23b.S antibody
- 背景
- Nucleotide excision repair (NER) is an essential element of DNA repair which eliminates unrelated DNA base lesions, including those induced by UV irradiation or chemicals. Although well defined in prokaryotes, eukaryotic NER is complex and involves at least two distinct subpathways. The transcription-coupled repair subpathway eliminates DNA lesions just prior to transcription. This is important for the removal of lesions for which the second pathway, global genome repair (i.e. covers the entire genome), is unable to repair. Individuals with defects in both pathways may suffer from xeroderma pigmentosum (XP), a condition with increased incidence of cancer in skin and internal organs. Mutations in seven genes result in human XP. However, one of these, XP-C, affects only the global genome repair pathway. The XP-C protein interacts with hHR23B, the human homolog of RAD23, an essential component of yeast NER. The XPC-hHR23B complex is required for excision of thymine dimers. In addition, hHR23B contains an N-terminal ubiquitin-like domain that allows for proteasome interaction. Thus, hHR23B may be an essential component of NER and mechanisms of DNA repair. This antibody is routinely tested by western blot analysis.
- 分子量
- 58 kDa
- 途径
- DNA Damage Repair
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