Dynamitin 抗体 (AA 55-196)
(5 references)-
- 抗原 See all Dynamitin (DCTN2) 抗体
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
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抗原表位
- AA 55-196
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适用
- 人, 小鼠, 大鼠, Blow Fly
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Dynamitin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠, 小鼠, Insect
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Dynactin p50 aa. 55-196
- 克隆位点
- 25-Dynactin p50
- 亚型
- IgG1
- Top Product
- Discover our top product DCTN2 Primary Antibody
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anti-Dynactin 2 (p50) (DCTN2) antibody
DCTN2 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 1-401) antibodyDCTN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 302-401) antibodyDCTN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 50-320) antibodyDCTN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 1-252) antibodyDCTN2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (AA 1-401) antibodyDCTN2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (C-Term) antibodyDCTN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynactin 2 (p50) (DCTN2) (N-Term) antibodyDCTN2 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 非洲爪蟾, 小鸡, 斑马鱼, Hamster, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968537, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling." in: Oncogene, Vol. 21, Issue 13, pp. 1945-54, (2002) (PubMed).
: "beta III spectrin binds to the Arp1 subunit of dynactin." in: The Journal of biological chemistry, Vol. 276, Issue 39, pp. 36598-605, (2001) (PubMed).
: "ZW10 helps recruit dynactin and dynein to the kinetochore." in: The Journal of cell biology, Vol. 142, Issue 3, pp. 763-74, (1998) (PubMed).
: "Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution." in: The Journal of cell biology, Vol. 139, Issue 2, pp. 469-84, (1997) (PubMed).
: "Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis." in: The Journal of cell biology, Vol. 132, Issue 4, pp. 617-33, (1996) (PubMed).
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: "Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling." in: Oncogene, Vol. 21, Issue 13, pp. 1945-54, (2002) (PubMed).
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- 抗原
- Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
- 别名
- Dynactin p50 (DCTN2 产品)
- 别名
- DCTN2 antibody, dctn2 antibody, dctn50 antibody, dynamitin antibody, rbp50 antibody, CG8269 antibody, DMN antibody, Dmel\\CG8269 antibody, P50 antibody, dDyn antibody, dmn antibody, dyna antibody, l(2)k16109 antibody, l(2)k16218 antibody, p50 antibody, p50/Dmn antibody, p50/dynamitin antibody, 2310042E05Rik antibody, C130077D06Rik antibody, C87049 antibody, DCTN-50 antibody, GMP23-48K antibody, RBP50 antibody, DCTN50 antibody, DYNAMITIN antibody, zgc:63867 antibody, dynactin subunit 2 antibody, dynactin subunit 2 S homeolog antibody, Dynactin 2, p50 subunit antibody, dynactin 2 antibody, dynactin 2 (p50) antibody, dynactin subunit 2 L homeolog antibody, DCTN2 antibody, dctn2.S antibody, DCTN2-p50 antibody, dctn2 antibody, Dctn2 antibody, dctn2.L antibody
- 背景
- Dyneins are ubiquitous, multimeric proteins that are responsible for minus end-directed microtubule-based organelle transport. They are divided into two classes, cytosolic and axonemal. The activity of cytosolic dynein is regulated by the multiprotein dynactin complex with which it co-purifies. Dynactin is composed of at least nine polypeptides with p50 being the second most abundant subunit. The complex consists of an F-actin-like core filament of actin-related protein Arp1, a heterodimer that acts as a cap at one end, and a 62kDa subunit at the other end. p150[glued] is the largest subunit of the complex. The precise function of dynactin remains to be determined, but it may be recruited to prometaphase kinetochores to assist in alignment and spindle organization during mitosis. Additionally, dynactin localizes at the tail of cytosolic dynein and activates dynein-mediated vesicle movement. Therefore, dynactin may function to anchor or target dynein to the kinetochore during mitosis.
- 分子量
- 50 kDa
- 途径
- M Phase, Ribonucleoprotein Complex Subunit Organization
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