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TGOLN2 抗体 (AA 31-244)

TGOLN2 适用: 大鼠 WB, IF 宿主: 小鼠 Monoclonal 2-TGN38 unconjugated
产品编号 ABIN968238
发货至: 中国
  • 抗原 See all TGOLN2 抗体
    TGOLN2 (Trans-Golgi Network Protein 2 (TGOLN2))
    抗原表位
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-244
    适用
    • 40
    • 7
    • 5
    • 2
    • 1
    • 1
    大鼠
    宿主
    • 36
    • 5
    • 2
    小鼠
    克隆类型
    • 30
    • 11
    单克隆
    标记
    • 28
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGOLN2 antibody is un-conjugated
    应用范围
    • 35
    • 13
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat TGN38 aa. 31-244
    克隆位点
    2-TGN38
    亚型
    IgG1
    Top Product
    Discover our top product TGOLN2 Primary Antibody
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Mary, Charrasse, Meriane, Comunale, Travo, Blangy, Gauthier-Rouvière: "Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism." in: Molecular biology of the cell, Vol. 13, Issue 1, pp. 285-301, (2002) (PubMed).

    Ozawa, Kondo, Hori, Kitao, Stern, Eisenmenger, Ogawa, Ohshima: "Expression of the oxygen-regulated protein ORP150 accelerates wound healing by modulating intracellular VEGF transport." in: The Journal of clinical investigation, Vol. 108, Issue 1, pp. 41-50, (2001) (PubMed).

    Xu, Shen, Joseph, Bryant, Luo, Frankel, Rotunda, Foster: "Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomains." in: Biochemical and biophysical research communications, Vol. 273, Issue 1, pp. 77-83, (2000) (PubMed).

    Humphrey, Peters, Yuan, Bonifacino: "Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence." in: The Journal of cell biology, Vol. 120, Issue 5, pp. 1123-35, (1993) (PubMed).

  • 抗原
    TGOLN2 (Trans-Golgi Network Protein 2 (TGOLN2))
    别名
    TGN38 (TGOLN2 产品)
    别名
    TGN38B antibody, TGN41 antibody, TGN46 antibody, Ttgn2 antibody, TGN38 antibody, TGN48 antibody, TGN51 antibody, TTGN2 antibody, TGOLN2 antibody, DKFZp469D101 antibody, Tgn38 antibody, Tgoln1 antibody, Ttgn1 antibody, trans-golgi network protein 2 antibody, Tgoln2 antibody, TGOLN2 antibody
    背景
    Newly synthesized proteins exit the ER and move to the cis-Golgi network (CGN) where they traverse the cis-medial and trans-cisternae before reaching the trans-Golgi network (TGN). N-linked oligosaccharide processing occurs in the TGN, and proteins are sorted to the plasma membrane, lysosomes, endosomes, and secretory granules. TGN38 is a type I integral membrane protein primarily localized to the TGN. It is involved in the sorting of nascent proteins into individual carrier vesicles for transport to appropriate destinations. It is thought to heterodimerize with TGN41 and participate in exocytic budding from the TGN. TGN38 has a molecular weight of 85 to 95 kDa. The core polypeptide represents approximately 38 kDa, while the remainder is accounted for by N- and O-linked oligosaccharide chains. A 286 aa N-terminal lumenal domain, a 21 aa membrane spanning domain, and a 33 aa C-terminal cytoplasmic tail comprise the structure of TGN38. The cytoplasmic tail contains a tyrosine-based motif, YQRL, that is thought to be involved in TGN localization. Therefore, TGN38 mediates the localization of various proteins to the TGN and serves as a TGN retrieval signal. This antibody is routinely tested by western blot analysis.
    Synonyms: Trans Golgi Network-38
    分子量
    85-95 kDa
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