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TFCP2 抗体 (AA 205-414)

TFCP2 适用: 人, 小鼠, 大鼠, 犬 WB, IF 宿主: 小鼠 Monoclonal 14-LSF unconjugated
产品编号 ABIN968193
发货至: 中国
  • 抗原 See all TFCP2 抗体
    TFCP2 (Transcription Factor CP2 (TFCP2))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 205-414
    适用
    • 33
    • 21
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬
    宿主
    • 28
    • 6
    小鼠
    克隆类型
    • 31
    • 3
    单克隆
    标记
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFCP2 antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 10
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    小鼠, 大鼠, 犬
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human LSF aa. 205-414
    克隆位点
    14-LSF
    亚型
    IgG1
    Top Product
    Discover our top product TFCP2 Primary Antibody
  • 说明

    Related Products: ABIN968551, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Volker, Rameh, Zhu, DeCaprio, Hansen: "Mitogenic stimulation of resting T cells causes rapid phosphorylation of the transcription factor LSF and increased DNA-binding activity." in: Genes & development, Vol. 11, Issue 11, pp. 1435-46, (1997) (PubMed).

    Shirra, Zhu, Huang, Pallas, Hansen: "One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs." in: Molecular and cellular biology, Vol. 14, Issue 8, pp. 5076-87, (1994) (PubMed).

  • 抗原
    TFCP2 (Transcription Factor CP2 (TFCP2))
    别名
    LSF (TFCP2 产品)
    别名
    cp2 antibody, lsf antibody, sef antibody, lbp-1c antibody, tfcp2c antibody, MGC75945 antibody, TFCP2 antibody, lbp1c antibody, lsf1d antibody, TCFCP2 antibody, LBP1C antibody, LSF antibody, LSF1D antibody, SEF antibody, TFCP2C antibody, CP-2 antibody, CP2 antibody, D230015P20Rik antibody, LBP-1c antibody, LBP-1d antibody, LBP1 antibody, Tcfcp2 antibody, UBP-1 antibody, transcription factor CP2 antibody, transcription factor CP2 L homeolog antibody, tfcp2 antibody, TFCP2 antibody, tfcp2.L antibody, Tfcp2 antibody
    背景
    LSF (alphaCP2 or LBP-1c) is a transcription factor originally identified by its binding to, and induction of, the SV40 late promoter. LSF displays some similarity to the Elf-1/NTF transcription factors of Drosophila. It is primarily found in its dimeric form in solution, however it is the tetrameric form that recognizes a center-to-center 10 bp repeat. LSF-1D (LBP-1d) is the product of an alternative splicing event, resulting in a deletion of a 51 amino acid segment that corresponds with the DNA-binding region of LSF. LSF-1D is found in the cytoplasm, not in the nucleus, and can interact with LSF to form a heterotetramer that can interfere with LSF DNA binding. In mitogen-stimulated human peripheral T cells, LSF is phosphorylated on amino acid 291, which increases its DNA binding activity. Thus, LSF-mediated gene transcription is regulated by its phosphorylation and/or its interaction with LSF-1D during cell growth. This antibody is routinely tested by western blot analysis.
    Synonyms: alphaCP2, LBP-1c
    分子量
    63 kDa
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