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ARF3 抗体 (AA 1-181)

ARF3 适用: 人, 大鼠, 小鼠, 小鸡, 犬, Frog WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 41-ARF3 unconjugated
产品编号 ABIN968175
发货至: 中国
  • 抗原 See all ARF3 抗体
    ARF3 (ADP-Ribosylation Factor 3 (ARF3))
    抗原表位
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-181
    适用
    人, 大鼠, 小鼠, 小鸡, 犬, Frog
    宿主
    • 20
    • 1
    小鼠
    克隆类型
    • 20
    单克隆
    标记
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARF3 antibody is un-conjugated
    应用范围
    • 14
    • 10
    • 9
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    大鼠, 小鼠, 小鸡, 犬, Frog
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human ARF3 aa. 1-181
    克隆位点
    41-ARF3
    亚型
    IgG1
    Top Product
    Discover our top product ARF3 Primary Antibody
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Lee, Stevens, Hsu, Tsai, Lee, Moss, Vaughan: "Expression in human endothelial cells of ADP-ribosylation factors, 20-kDa guanine nucleotide-binding proteins involved in the initiation of vesicular transport." in: Journal of molecular and cellular cardiology, Vol. 28, Issue 9, pp. 1911-20, (1997) (PubMed).

    Morinaga, Tsai, Moss, Vaughan: "Isolation of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP ribosylation factor (ARF) 1 and ARF3 that contains a Sec7-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 23, pp. 12856-60, (1996) (PubMed).

    Cockcroft, Thomas, Fensome, Geny, Cunningham, Gout, Hiles, Totty, Truong, Hsuan: "Phospholipase D: a downstream effector of ARF in granulocytes." in: Science (New York, N.Y.), Vol. 263, Issue 5146, pp. 523-6, (1994) (PubMed).

    Moss, Vaughan: "ADP-ribosylation factors, 20,000 M(r) guanine nucleotide-binding protein activators of cholera toxin and components of intracellular vesicular transport systems." in: Cellular signalling, Vol. 5, Issue 4, pp. 367-79, (1993) (PubMed).

    Kahn, Radding: "Separation of the presynaptic and synaptic phases of homologous pairing promoted by recA protein." in: The Journal of biological chemistry, Vol. 259, Issue 12, pp. 7495-503, (1984) (PubMed).

  • 抗原
    ARF3 (ADP-Ribosylation Factor 3 (ARF3))
    别名
    ARF3 (ARF3 产品)
    别名
    5430400P17Rik antibody, AI854770 antibody, arf3 antibody, MGC76217 antibody, MGC79549 antibody, ARF3 antibody, ADP-ribosylation factor 3 antibody, ARF-LIKE 1 antibody, ARL1 antibody, ATARL1 antibody, F27A10.8 antibody, ARF1 antibody, si:dz202l16.1 antibody, wu:fc66h11 antibody, zgc:92190 antibody, ADP ribosylation factor 3 antibody, ADP-ribosylation factor 3 antibody, ADP ribosylation factor 1 antibody, ADP ribosylation factor 3 S homeolog antibody, ADP-ribosylation factor 3b antibody, ADP-ribosylation factor 3a antibody, ARF3 antibody, Arf3 antibody, arf1 antibody, arf3.S antibody, arf3b antibody, arf3a antibody
    背景
    The ADP-ribosylation factors (ARFs) belong to the multigene family of small GTPases capable of activating cholera toxin. ARFs fall into three different classes: Class I is composed of ARF-1, ARF-2, and ARF-3, Class II consists of ARF-4 and ARF-5, and Class III includes ARF6. Unique to ARFs is their lack of intrinsic GTP hydrolysis activity, a high affinity for GDP in a Mg2+-dependent manner, and phospholipid requirement for nucleotide exchange. ARFs are involved in intravesicular acidification of microsomal vesicles, endosome fusion, nuclear membrane assembly, and formation of clathrin-coated vesicles. In addition, GTP and ARF-3 are required for the activation of phospholipase D (PLD), an early cellular response triggered by the binding of receptors on the cell surface in response to numerous extracellular signals. Although predominantly cytosolic, ARF-3 can be translocated to cellular membranes upon cellular stimulation. The transition between the GDP-bound ARF-3 to the GTP-ARF-3 is facilitated by a high molecular weight guanine nucleotide-exchange factor sensitive to brefeldin. ARF-3 has been reported to be the most abundant in brain, kidney, and liver.
    Synonyms: ADP Ribosylation Factor-3
    分子量
    20 kDa
    途径
    Inositol Metabolic Process, Cellular Glucan Metabolic Process
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