MEF2D 抗体 (AA 346-511)
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- 抗原 See all MEF2D 抗体
- MEF2D (Myocyte Enhancer Factor 2D (MEF2D))
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抗原表位
- AA 346-511
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MEF2D antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse MEF2D aa. 346-511
- 克隆位点
- 9-MEF2D
- 亚型
- IgG1
- Top Product
- Discover our top product MEF2D Primary Antibody
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anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 299-509) antibody
MEF2D 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 1-521) antibodyMEF2D 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 256-351) antibodyMEF2D 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 1-110) antibodyMEF2D 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 1-521) antibodyMEF2D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 256-351) antibodyMEF2D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (AA 256-351) antibodyMEF2D 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D6 unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (pSer180) antibodyMEF2D 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (pSer444) antibodyMEF2D 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2D (MEF2D) (C-Term) antibodyMEF2D 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, Pig, 马, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia." in: Science (New York, N.Y.), Vol. 289, Issue 5488, pp. 2363-6, (2000) (PubMed).
: "The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter." in: The Journal of biological chemistry, Vol. 275, Issue 21, pp. 16323-8, (2000) (PubMed).
: "A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage." in: Development (Cambridge, England), Vol. 118, Issue 4, pp. 1095-106, (1994) (PubMed).
: "A Mef2 gene that generates a muscle-specific isoform via alternative mRNA splicing." in: Molecular and cellular biology, Vol. 14, Issue 3, pp. 1647-56, (1994) (PubMed).
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: "NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia." in: Science (New York, N.Y.), Vol. 289, Issue 5488, pp. 2363-6, (2000) (PubMed).
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- 抗原
- MEF2D (Myocyte Enhancer Factor 2D (MEF2D))
- 别名
- MEF2D (MEF2D 产品)
- 别名
- sl1 antibody, sl-1 antibody, XMEF2D antibody, MGC145245 antibody, C80750 antibody, myocyte enhancer factor 2D antibody, MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) antibody, mef2d antibody, MEF2D antibody, Mef2d antibody
- 背景
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MEF2D is a member of the MEF2 (Myocyte-specific Enhancer-binding Factor 2) transcription factor family. Members of this family (MEF2A, B, C, & D) contain several characteristic motifs that include a MEF2 domain and a MADS box. MEF2 proteins bind the DNA sequence, 5'- (C/T)T(A/T)(A/T)AAATA(A/G)-3', and binding occurs primarily, although not exclusively, in muscle cells. MEF2D gene expression is ubiquitous and the mRNA is alternatively spliced. This results in multiple protein isoforms that heterodimerize with other family members. In addition to the MEF2 and MADS domains, MEF2D has a glutamine-/proline-rich region, amino acids 365-404, and a basic region, in the MADS domain near the N-terminus. The glutamine-/proline-rich region is involved in transactivation, while the basic region mediates sequence-specific DNA binding. MEF2D displays 75% similarity to hMEF2A and hMEF2C. Myogenin gene transcription requires MEF2D, indicating that MEF2D is involved in myogenesis and muscle cell differentiation. MEF2D has been reported to have a calculated molecular weight of 56 kD, but can be observed migrating in a range of 56-70 kD.
Synonyms: Myocyte-specific Enhancer-binding Factor 2 - 分子量
- 56-70 kDa
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