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NAT1 抗体 (AA 672-830)

NAT1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, IHC, IP, IF 宿主: 小鼠 Monoclonal 35-T1 unconjugated
产品编号 ABIN968148
发货至: 中国
  • 抗原 See all NAT1 抗体
    NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 672-830
    适用
    人, 小鼠, 大鼠, Cow, 犬
    宿主
    • 42
    • 2
    • 1
    小鼠
    克隆类型
    • 45
    单克隆
    标记
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NAT1 antibody is un-conjugated
    应用范围
    • 30
    • 24
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    交叉反应
    小鼠, 大鼠, 犬, 牛
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human NAT1 aa. 672-830
    克隆位点
    35-T1
    亚型
    IgG1
    Top Product
    Discover our top product NAT1 Primary Antibody
  • 说明

    Related Products: ABIN968535, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Henis-Korenblit, Strumpf, Goldstaub, Kimchi: "A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation." in: Molecular and cellular biology, Vol. 20, Issue 2, pp. 496-506, (2000) (PubMed).

    Yamanaka, Poksay, Arnold, Innerarity: "A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme." in: Genes & development, Vol. 11, Issue 3, pp. 321-33, (1997) (PubMed).

  • 抗原
    NAT1 (N-Acetyltransferase 1 (Arylamine N-Acetyltransferase) (NAT1))
    别名
    NAT1 (NAT1 产品)
    别名
    AAC1 antibody, MNAT antibody, NAT-1 antibody, NATI antibody, Nat-1 antibody, Nat antibody, NAT1 antibody, AT-I antibody, N-acetyltransferase 1 antibody, N-acetyl transferase 1 antibody, N-acetyltransferase 1 (arylamine N-acetyltransferase) antibody, arylamine N-acetyltransferase 1-like antibody, NAT1 antibody, Nat1 antibody, LOC101095575 antibody
    背景
    EIF-4 proteins are required for recognition of mRNA and acceleration of protein translation. This group of proteins consists of the RNA helicase eIF-4A, the RNA-binding protein eIF-4B, the cap-binding protein eIF-4E, and eIF-4G (p220). NAT1 (Novel APOBEC-1 Target no. 1), also known as DAP-5 (Death Associated Protein -5), is homologous to eIF-4G. Amino acid sequence comparison of NAT1 and eIF-4 shows that NAT1 lacks an eIF-4G N-terminal region. This region mediates eIF-4G association with eIF-4E. The highest degree of homology is within the central portions of NAT1 and eIF-4G, while the lowest degree of homology occurs at the C-terminus. NAT1 more closely resembles a cleaved form of eIF-4G that is involved in cap-independent translation. It is thought that NAT1 is involved in the repression of translation via its inhibition of both cap-dependent and cap-independent translation.
    Synonyms: Novel APOBEC-1 Target no. 1, DAP-5, Death Associated Protein -5
    分子量
    100 kDa
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