PKN1 抗体 (AA 215-388)
(4 references)-
- 抗原 See all PKN1 抗体
- PKN1 (Protein Kinase N1 (PKN1))
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抗原表位
- AA 215-388
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PKN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 犬, 大鼠, 小鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human PRK1 aa. 215-388
- 克隆位点
- 49-PRK1
- 亚型
- IgG1
- Top Product
- Discover our top product PKN1 Primary Antibody
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anti-Protein Kinase N1 (PKN1) (AA 462-615) antibody
PKN1 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Protein Kinase N1 (PKN1) (AA 442-620) antibodyPKN1 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4H10B1 unconjugated
anti-Protein Kinase N1 (PKN1) (AA 1-300) antibodyPKN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N1 (PKN1) (AA 615-874) antibodyPKN1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N1 (PKN1) (AA 836-870) antibodyPKN1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB56692 unconjugated
anti-Protein Kinase N1 (PKN1) (AA 1-942) antibodyPKN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N1 (PKN1) (Internal Region) antibodyPKN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase N1 (PKN1) (AA 1-942) antibodyPKN1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase N1 (PKN1) (Center) antibodyPKN1 适用: 人, 小鼠, Cow, 猴 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22974-9, (2002) (PubMed).
: "Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase." in: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11064-70, (2000) (PubMed).
: "Cloning and expression patterns of two members of a novel protein-kinase-C-related kinase family." in: European journal of biochemistry / FEBS, Vol. 227, Issue 1-2, pp. 344-51, (1995) (PubMed).
: "Activation of PKN, a novel 120-kDa protein kinase with leucine zipper-like sequences, by unsaturated fatty acids and by limited proteolysis." in: Biochemical and biophysical research communications, Vol. 204, Issue 1, pp. 348-56, (1994) (PubMed).
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: "Detecting protein-phospholipid interactions. Epidermal growth factor-induced activation of phospholipase D1b in situ." in: The Journal of biological chemistry, Vol. 277, Issue 25, pp. 22974-9, (2002) (PubMed).
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- 抗原
- PKN1 (Protein Kinase N1 (PKN1))
- 别名
- PRK1 (PKN1 产品)
- 别名
- DBK antibody, PAK-1 antibody, PAK1 antibody, PKN antibody, PKN-ALPHA antibody, PRK1 antibody, PRKCL1 antibody, F730027O18Rik antibody, Pkn antibody, Prkcl1 antibody, Stk3 antibody, PKN1 antibody, 3-2 antibody, CG2049 antibody, CG2055 antibody, CT6637 antibody, CT6660 antibody, DPKN antibody, Dmel\\CG2049 antibody, Dpkn antibody, PRK2 antibody, Pk45C antibody, Pk?3 antibody, dPKN antibody, l(2)06736 antibody, l(2)45Ca antibody, v(2)rG232 antibody, protein kinase N1 antibody, protein kinase N1b antibody, Protein kinase N antibody, PKN1 antibody, Pkn1 antibody, pkn1b antibody, pkn1 antibody, Pkn antibody
- 背景
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Members of the Protein Kinase C (PKC) family of homologous serine/threonine protein kinases are involved in a number of processes such as cell growth, cell differentiation, and cytokine secretion. PKCs are activated by Ca2+, phospholipids, diacylglycerol, phorbol esters, and proteolysis. PRK1 (PKC-Related Kinase 1, also named PKN) was originally identified in human hippocampus as a novel protein kinase with sequence homology to PKC. PRK1 contains 942 amino acids with an apparent molecular weight of 120 kDa. Although activated by limited proteolysis, PRK1 is not activated by Ca2+/diacylglycerol or phorbol esters. However, PRK1 is activated by phospholipids and arachidonic acid. PRK1 may regulate cytoskeletal changes since it binds to Rho-GTP and becomes phosphorylated in vivo, coincidentally with the formation of focal adhesions and stress fibers.
Synonyms: PKN - 分子量
- 120 kDa
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