TRADD 抗体 (AA 163-312)
(4 references)-
- 抗原 See all TRADD 抗体
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
-
抗原表位
- AA 163-312
-
适用
- 人, 大鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TRADD antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 大鼠
- 产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human TRADD aa. 163-312
- 克隆位点
- 37-TRADD
- 亚型
- IgG1
- Top Product
- Discover our top product TRADD Primary Antibody
-
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibodyTRADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibodyTRADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A1E8 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibodyTRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18788 unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibodyTRADD 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibodyTRADD 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibodyTRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
- 说明
-
Related Products: ABIN968537, ABIN967389
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
-
-
: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).
: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, (2002) (PubMed).
: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, (2001) (PubMed).
: "Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD." in: The Journal of biological chemistry, Vol. 271, Issue 16, pp. 9858-62, (1996) (PubMed).
-
: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).
-
- 抗原
- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
- 别名
- TRADD (TRADD 产品)
- 别名
- TRADD antibody, Hs.89862 antibody, 9130005N23Rik antibody, AA930854 antibody, wu:fc59e02 antibody, zgc:103556 antibody, tradd antibody, TNFRSF1A associated via death domain antibody, conjugal transfer protein D antibody, TNFRSF1A-associated via death domain antibody, TNFRSF1A-associated via death domain L homeolog antibody, tnfrsf1a-associated via death domain antibody, TRADD antibody, traDd antibody, Tradd antibody, tradd.L antibody, tradd antibody
- 背景
-
TNFalpha (Tumor Necrosis Factor) stimulates programmed cell death and NF-kappaB activation as a result of its binding to the TNF receptor 1 (TNFR1). Within this receptor, a sequence referred to as the death domain” has been shown to be necessary for both of these functions. Using the yeast two-hybrid system to detect proteins which interact with the receptor through this death domain”, a 34 kDa protein was found and designated TRADD (TNFR1-Associated Death Domain protein). TRADD appears to contain no intrinsic catalytic activity. It also contains a death domain and it has been shown to bind to FADD and RIP. Mutational analysis of TRADD demonstrates that programmed cell death and NF-kappaB activation are distinct and controlled independently.
Synonyms: TNFR1-Associated Death Domain protein - 分子量
- 34 kDa
- 途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
-
