NUMA1 抗体 (AA 10-189)
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- 抗原 See all NUMA1 抗体
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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抗原表位
- AA 10-189
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NUMA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 小鼠, 大鼠, 小鸡, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human NuMA aa. 10-189
- 克隆位点
- 22-NuMA
- 亚型
- IgM
- Top Product
- Discover our top product NUMA1 Primary Antibody
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- 说明
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Related Products: ABIN968535, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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Recruitment of dioxin receptor to active transcription sites." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2001-15, (2002) (PubMed).
: "Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor." in: Oncogene, Vol. 20, Issue 35, pp. 4853-63, (2001) (PubMed).
: "A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract." in: The Journal of cell biology, Vol. 149, Issue 3, pp. 531-6, (2000) (PubMed).
: "NuMA: an unusually long coiled-coil related protein in the mammalian nucleus." in: The Journal of cell biology, Vol. 116, Issue 6, pp. 1303-17, (1992) (PubMed).
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Recruitment of dioxin receptor to active transcription sites." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2001-15, (2002) (PubMed).
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- 抗原
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- 别名
- NuMA (NUMA1 产品)
- 别名
- NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
- 背景
- NuMA (Nuclear Mitotic Apparatus protein) is a 2115 amino acid protein with a coiled-coil structure similar to that of myosins and intermediate filaments. Indirect immunofluorescence assays indicate that NuMA's localization is very dynamic. During interphase, NuMA is in the nucleus and during mitosis it moves to the polar regions of the mitotic spindle. NuMA is a very abundant phosphoprotein and antibodies to this protein are often found in patients with autoimmune diseases. Although NuMA is thought to be a structural component of the nucleus, the precise cellular function for this protein is still unknown.
- 分子量
- 238-290 kDa
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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