PP2A Catalytic alpha (AA 153-309) 抗体
适用: 犬, 人, 小鼠, 大鼠
IF, IP, IHC, WB
宿主: 小鼠
Monoclonal
46
unconjugated
(5 references)-
- 抗原
- PP2A Catalytic alpha
- 抗原表位
- AA 153-309
- 适用
- 犬, 人, 小鼠, 大鼠
- 宿主
- 小鼠
- 克隆类型
- 单克隆
- 应用范围
- Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
- 交叉反应
- 犬, 大鼠, 小鼠
- 产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human PP2A aa. 153-309
- 克隆位点
- 46
- 亚型
- IgG1
-
- 说明
-
Related Products: ABIN968533, ABIN967389
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
-
-
: "Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na+,K+-ATPase endocytosis." in: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44108-14, (2002) (PubMed).
: "Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex." in: The Journal of cell biology, Vol. 158, Issue 5, pp. 967-78, (2002) (PubMed).
: "Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 444-53, (2002) (PubMed).
: "Protein phosphatase 2A interacts with and directly dephosphorylates RelA." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 47828-33, (2001) (PubMed).
: "Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts." in: The Journal of biological chemistry, Vol. 269, Issue 11, pp. 7957-62, (1994) (PubMed).
-
: "Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na+,K+-ATPase endocytosis." in: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44108-14, (2002) (PubMed).
-
- 抗原
- PP2A Catalytic alpha
- 背景
- Protein phosphatases of the type 2A (PP2A) are composed of two regulatory and one catalytic subunit. The different subunits are encoded by multiple genes. PP2A are specific for phosphoserine and phosphothreonine residues of proteins that are involved in the regulation of cellular growth. PP2A binds and dephosphorylates the middle T antigens of polyoma virus. This interaction may regulate the transcriptional activity of the virus. The 36 kDa catalytic subunit is rapidly tyrosine phosphorylated as a result of growth factor stimulation or cell transformation. Tyrosine phosphorylation of the catalytic subunit may inactivate the phosphatase activity of PP2A.
- 分子量
- 36 kDa
-
You are here:
