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DLG4 抗体 (AA 353-504)

Name: DLG4 抗体 (AA 353-504)
SKU: ABIN968003
Availability: OutOfStock

DLG4 适用: 大鼠, 小鼠 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 16-PSD unconjugated

Western blot analysis of PSD-95 on a rat cerebrum lysate. (DLG4 抗体 (AA 353-504))

Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721). (DLG4 抗体 (AA 353-504))

Image no. 3 for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (AA 353-504) antibody (ABIN968003) (DLG4 抗体 (AA 353-504))

Western Blotting (WB) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (AA 353-504) antibody (ABIN968003) (DLG4 抗体 (AA 353-504))

4 images

(5 references)

产品编号 ABIN968003

发货至: 中国

Datasheet as PDF

抗原 See all DLG4 抗体

DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
抗原表位
16

16

16

16

7

7

7

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 353-504
适用
145

122

117

31

18

4

3

3

3

2

2

1

1

1

1

1
大鼠, 小鼠
宿主
102

64

1

1

1
小鼠
Compatible Secondaries
克隆类型
96

73
单克隆
标记
62

11

8

8

7

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2
This DLG4 antibody is un-conjugated
应用范围
123

65

45

40

40

31

25

24

22

20

16

9

7

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

交叉反应

小鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Rat PSD-95 aa. 353-504

克隆位点

16-PSD

亚型

IgG1

Top Product

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anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibody
DLG4 适用: 大鼠, 小鼠, 人 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 HRP

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 FITC

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Alkaline Phosphatase (AP))
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 Alkaline Phosphatase (AP)

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 Biotin

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 PE

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 APC

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)
DLG4 适用: 大鼠 WB, IHC, IF, ICC, AA 宿主: 小鼠 Monoclonal 7E3 PerCP

说明

Related Products: ABIN968545, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Fagiolini, Katagiri, Miyamoto, Mori, Grant, Mishina, Hensch: "Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 5, pp. 2854-9, (2003) (PubMed).

Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).

Mehta, Wu, Garner, Marshall: "Molecular mechanisms regulating the differential association of kainate receptor subunits with SAP90/PSD-95 and SAP97." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16092-9, (2001) (PubMed).

Brenman, Chao, Gee, McGee, Craven, Santillano, Wu, Huang, Xia, Peters, Froehner, Bredt: "Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains." in: Cell, Vol. 84, Issue 5, pp. 757-67, (1996) (PubMed).

Cho, Hunt, Kennedy: "The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein." in: Neuron, Vol. 9, Issue 5, pp. 929-42, (1992) (PubMed).
抗原

DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

别名

PSD-95 (DLG4 产品)

别名

11 antibody, CG1725 antibody, CG1730 antibody, CPD antibody, DLG antibody, DLG-A antibody, Discs-large antibody, Dlg antibody, Dlg-A antibody, Dlg1 antibody, DlgA antibody, Dmel\\CG1725 antibody, Drodlg antibody, PSD95 antibody, SAP97 antibody, anon-EST:Posey93 antibody, anon-WO03040301.258 antibody, anon-WO03040301.260 antibody, anon-WO03040301.268 antibody, d. lg.-1 antibody, dlg antibody, dlg-1 antibody, dlg-A antibody, dlgA antibody, dlgS97 antibody, l(1)10Bf antibody, l(1)G0276 antibody, l(1)G0342 antibody, l(1)G0456 antibody, l(1)G19 antibody, l(1)L11 antibody, l(1)bwn antibody, l(1)d.lg-1 antibody, l(1)d.lg.-1 antibody, l(1)discs large antibody, l(1)dlg antibody, l(1)dlg-1 antibody, l(1)dlg1 antibody, l(1)l.pr.-2 antibody, l(1)lpr-2 antibody, misb antibody, dlgh4 antibody, psd95 antibody, sap90 antibody, sap-90 antibody, LLGL1 antibody, Dlgh4 antibody, PSD-95 antibody, SAP90 antibody, SAP90A antibody, Sap90 antibody, SAP-90 antibody, DLG4 antibody, discs large 1 antibody, discs, large homolog 4 antibody, discs large MAGUK scaffold protein 4 antibody, discs, large homolog 4b (Drosophila) antibody, discs, large homolog 4 (Drosophila) antibody, dlg1 antibody, dlg4 antibody, DLG4 antibody, dlg4b antibody, Dlg4 antibody

背景

PostSynaptic Density (PSD) refers to a dense region of submembranous cytoskeleton found most prominently in postsynaptic membranes of the CNS. Possible functions for the PSD include regulation and aggregation of receptors, structural stabilization of the synaptic junction, and transduction of signals from membrane receptors. Some of the proteins associated with the PSD are fodrin, tubulin, calmodulin, CaM Kinase II, PSD-95, and PSD-93. PSD-95 (SAP90) is a protein that interacts with the NMDA receptor NMDAR2B, neuronal NOS (nNOS or bNOS), and other proteins. PSD-95 contains one SH3 domain in its carboxy-terminal domain, as well as three conserved repeat regions called GLGF or PDZ domains. nNOS, which is concentrated in synaptic junctions, also contains a PZD domain. PSD-95 and nNOS interact via their respective PZD domains, which may mediate the binding of nNOS to skeletal muscle syntrophin. This antibody is routinely tested by western blot analysis.
Synonyms: PostSynaptic Density-95, SAP90

分子量

95 kDa

途径

Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity