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EPH Receptor A4 抗体 (AA 279-472)

EPHA4 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 35-EphA4 unconjugated
产品编号 ABIN967994
发货至: 中国
  • 抗原 See all EPH Receptor A4 (EPHA4) 抗体
    EPH Receptor A4 (EPHA4)
    抗原表位
    • 15
    • 11
    • 9
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 279-472
    适用
    • 77
    • 36
    • 22
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡
    宿主
    • 93
    • 5
    • 1
    小鼠
    克隆类型
    • 91
    • 6
    • 1
    单克隆
    标记
    • 45
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EPH Receptor A4 antibody is un-conjugated
    应用范围
    • 58
    • 50
    • 36
    • 13
    • 13
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    大鼠, 人, 犬, 小鸡
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Mouse Sek aa. 279-472
    克隆位点
    35-EphA4
    亚型
    IgG1
    Top Product
    Discover our top product EPHA4 Primary Antibody
  • 说明

    Related Products: ABIN967389, ABIN968545

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Ellis, Kasmi, Ganju, Walls, Panayotou, Reith: "A juxtamembrane autophosphorylation site in the Eph family receptor tyrosine kinase, Sek, mediates high affinity interaction with p59fyn." in: Oncogene, Vol. 12, Issue 8, pp. 1727-36, (1996) (PubMed).

    Becker, Gilardi-Hebenstreit, Seitanidou, Wilkinson, Charnay: "Characterisation of the Sek-1 receptor tyrosine kinase." in: FEBS letters, Vol. 368, Issue 2, pp. 353-7, (1995) (PubMed).

    Gilardi-Hebenstreit, Nieto, Frain, Mattéi, Chestier, Wilkinson, Charnay: "An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain." in: Oncogene, Vol. 7, Issue 12, pp. 2499-506, (1993) (PubMed).

  • 抗原
    EPH Receptor A4 (EPHA4)
    别名
    EphA4 (EPHA4 产品)
    别名
    HEK8 antibody, SEK antibody, TYRO1 antibody, RGD1560587 antibody, ephe antibody, EPHA4 antibody, Ci-Eph1 antibody, sek antibody, hek8 antibody, rtk1 antibody, tyr01 antibody, 2900005C20Rik antibody, AI385584 antibody, Cek8 antibody, Hek8 antibody, Sek antibody, Sek1 antibody, Tyro1 antibody, rb antibody, XEpha4 antibody, sek-1 antibody, epha4 antibody, pag antibody, EphA4 antibody, apha3 antibody, ek2 antibody, epha3 antibody, sb:cb246 antibody, zek2 antibody, zgc:109882 antibody, EPH receptor A4 antibody, Eph receptor A4 antibody, ephrin receptor epsilon antibody, EPH receptor A4 S homeolog antibody, EPH receptor A4 L homeolog antibody, eph receptor A4a antibody, EPHA4 antibody, Epha4 antibody, ephe antibody, epha4 antibody, epha4.S antibody, epha4.L antibody, epha4a antibody
    背景
    EphA4/Sek is a glycosylated protein tyrosine kinase of 986 amino acids and an apparent 110-130kDa molecular weight (molecular weight depends on glycocylation level of protein). EphA4 belongs to the Eph subfamily of receptor tyrosine kinases and like many others, it has an amino-terminal ligand-binding domain exposed to the extracellar matrix. EphA4 is predominantly expressed during development (this is common in the Eph family) and because of its mRNA localization, it has been proposed that it may play a role during segmentation of the hindbrain and mesoderm. Tyrosine 602 is a major autophosphorylation site of EphA4 and appears to be the docking site for the intracellular tyrosine kinase fyn.
    分子量
    110-130 kDa
    途径
    RTK signaling
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