NOS2 抗体 (AA 961-1144)
(5 references)-
- 抗原 See all NOS2 抗体
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
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抗原表位
- AA 961-1144
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NOS2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse iNOS aa. 961-1144
- 克隆位点
- 54-iNOS
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product NOS2 Primary Antibody
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anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 14-100) antibody
NOS2 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4E5 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 43-213) antibodyNOS2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 518-694) antibodyNOS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (Thr177) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (C-Term) antibodyNOS2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 500-730) antibodyNOS2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibodyNOS2 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18210 unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibodyNOS2 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibodyNOS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968550, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Regulation of ICAM-1/CD54 expression on human endothelial cells by hydrogen peroxide involves inducible NO synthase." in: Journal of leukocyte biology, Vol. 67, Issue 3, pp. 327-34, (2000) (PubMed).
: "Unaltered vasoconstrictor responsiveness after iNOS inhibition in lungs from chronically hypoxic rats." in: The American journal of physiology, Vol. 276, Issue 1 Pt 1, pp. L122-30, (1999) (PubMed).
: "B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity." in: Blood, Vol. 92, Issue 3, pp. 1031-43, (1998) (PubMed).
: "Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta." in: The Journal of experimental medicine, Vol. 178, Issue 2, pp. 605-13, (1993) (PubMed).
: "Cloning and characterization of inducible nitric oxide synthase from mouse macrophages." in: Science (New York, N.Y.), Vol. 256, Issue 5054, pp. 225-8, (1992) (PubMed).
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: "Regulation of ICAM-1/CD54 expression on human endothelial cells by hydrogen peroxide involves inducible NO synthase." in: Journal of leukocyte biology, Vol. 67, Issue 3, pp. 327-34, (2000) (PubMed).
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- 抗原
- NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
- 别名
- iNOS/NOS Type II (NOS2 产品)
- 别名
- HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody
- 背景
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Nitric oxide synthase (NOS), a cell-type specific enzyme, catalyzes the synthesis of nitric oxide (NO). NO is a short-lived radical that transmits cellular signals involved in vasorelaxation, neurotransmission, and cytotoxicity. In macrophages and other cell types, NOS (iNOS or macNOS) activity increases following exposure to cytokines (IFN-gamma, TNF-alpha, and IL-1) and microbial products (lipopolysaccharide (LPS)). iNOS is activated independently of Ca2+/calmodulin and its level of expression is tightly controlled by several transcription factors, including NFkappaB. Data indicates that TGF-beta affects translation of iNOS mRNA and decreases iNOS protein stability. Normally undetectable in brain tissue, iNOS mRNA has been observed in CNS tissues of animals under experimental pathologic conditions. iNOS and nNOS share 51% amino acid homology with the greatest degree of divergence in the calmodulin binding domain. This antibody has been reported to cross-react with nNOS and eNOS.
Synonyms: NOS Type II - 分子量
- 130 kDa
- 途径
- Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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