我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Caveolin-1 抗体 (AA 1-178)

Name: Caveolin-1 抗体 (AA 1-178)
SKU: ABIN967951
Availability: OutOfStock

CAV1 适用: 人, 大鼠, 小鼠, 犬, 小鸡 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 2297-Caveolin 1 unconjugated

Western blot analysis of Caveolin 1 on a human endothelial cell lysate. (Caveolin-1 抗体 (AA 1-178))

Immunofluorescence with the mouse anti- caveolin 1 antibody on human endothelial cells. (Caveolin-1 抗体 (AA 1-178))

Image no. 3 for anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-178) antibody (ABIN967951) (Caveolin-1 抗体 (AA 1-178))

Western Blotting (WB) image for anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-178) antibody (ABIN967951) (Caveolin-1 抗体 (AA 1-178))

4 images

(5 references)

产品编号 ABIN967951

发货至: 中国

Datasheet as PDF

抗原 See all Caveolin-1 (CAV1) 抗体

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
抗原表位
15

14

8

7

4

4

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-178
适用
105

64

50

12

10

9

9

8

8

7

5

3

2

1

1

1

1

1

1

1

1

1

1
人, 大鼠, 小鼠, 犬, 小鸡
宿主
96

10

6

2
小鼠
Compatible Secondaries
克隆类型
95

19
单克隆
标记
79

7

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This Caveolin-1 antibody is un-conjugated
应用范围
89

36

27

20

20

16

16

16

11

9

4

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Please refer to us for technical protocols.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

RSV-CEF Caveolin aa. 1-178

克隆位点

2297-Caveolin 1

亚型

IgG1

Top Product

Discover our top product CAV1 Primary Antibody
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
KO Validated CAV1 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibody
CAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-105) antibody
CAV1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Internal Region) antibody
Verified CAV1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-100) antibody
CAV1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-120) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody
CAV1 适用: 人, 小鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibody
CAV1 适用: 人, 小鼠 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
CAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968536, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Woodman, Park, Cohen, Cheung, Chandra, Shirani, Tang, Jelicks, Kitsis, Christ, Factor, Tanowitz, Lisanti: "Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38988-97, (2002) (PubMed).

Ushio-Fukai, Hilenski, Santanam, Becker, Ma, Griendling, Alexander: "Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells: role of cholesterol-rich microdomains and focal adhesions in angiotensin II signaling." in: The Journal of biological chemistry, Vol. 276, Issue 51, pp. 48269-75, (2001) (PubMed).

Galbiati, Volonte, Brown, Weinstein, Ben-Zeev, Pestell, Lisanti: "Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains." in: The Journal of biological chemistry, Vol. 275, Issue 30, pp. 23368-77, (2000) (PubMed).

Breton, Lisanti, Tyszkowski, McLaughlin, Brown: "Basolateral distribution of caveolin-1 in the kidney. Absence from H+-atpase-coated endocytic vesicles in intercalated cells." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 46, Issue 2, pp. 205-14, (1998) (PubMed).

Conrad, Smart, Ying, Anderson, Bloom: "Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps." in: The Journal of cell biology, Vol. 131, Issue 6 Pt 1, pp. 1421-33, (1996) (PubMed).
抗原

Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

别名

Caveolin 1 (CAV1 产品)

别名

fc07c04 antibody, wu:fc07c04 antibody, Cav-1 antibody, bscl3 antibody, cav1 antibody, cav1a antibody, cgl3 antibody, vip21 antibody, cav1b antibody, caveolin-1 antibody, cav antibody, mstp085 antibody, Caveolin-1 antibody, CAV1 antibody, cav-1 antibody, Cav antibody, caveolin 1 antibody, BSCL3 antibody, CGL3 antibody, MSTP085 antibody, PPH3 antibody, VIP21 antibody, caveolin 1 antibody, caveolin 1 L homeolog antibody, caveolin 1 S homeolog antibody, caveolin 1, caveolae protein antibody, caveolin 1, caveolae protein, 22kDa antibody, Caveolin antibody, cav1 antibody, cav1.L antibody, cav1.S antibody, CAV1 antibody, Cav1 antibody, cav-1 antibody

背景

Identified as a tyrosine phosphorylated protein in Rous sarcoma virus-transformed chick embryo fibroblasts (CEF), caveolin is now known to be ubiquitously expressed. Caveolin (also known as VIP21) localizes to non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane. This transmembrane protein plays a structural role in these specializations. Caveolin is also present at the trans-Golgi network (TGN) and similar quantities are found in apically and basolaterally destined transport vesicles. Caveolin is part of a complex containing glycosylphosphatidylinositol (GPI)-linked molecules and cytoplasmic signaling proteins. Caveolin is a transmembrane adaptor molecule that can simultaneously recognize GPI-linked proteins and interact with downstream cytoplasmic signaling molecules, such as c-yes, Annexin II, and hetero-trimeric G proteins. Caveolin-1 can generate two forms, alpha and beta, due to alternate splicing of the mRNA. The alpha isoform has been reported to be observed at 24 kD and the beta isoform at 21 kD. Caveolin-1 forms large lipid-binding homo-oligomers which are believed to play a role in caveolae formation. It may also function as a scaffolding protein which concentrates andorganizes signaling molecules, a role supported by the fact that caveolin-1 interacts directly with inactive Ras and G-protein alpha subunits. This antibody is routinely tested by western blot analysis.

分子量

21-24 kDa

途径

Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals