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Flotillin 2 抗体 (AA 122-379)

Name: Flotillin 2 抗体 (AA 122-379)
SKU: ABIN967932
Availability: OutOfStock

FLOT2 适用: 人, 大鼠, 小鼠, 犬, 小鸡 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 29-Flotillin unconjugated

Western blot analysis of Flotillin-2 on human endothelial cell lysate. (Flotillin 2 抗体 (AA 122-379))

Immunofluorescent staining of WI38 cells. (Flotillin 2 抗体 (AA 122-379))

2 images

(5 references)

产品编号 ABIN967932

发货至: 中国

Datasheet as PDF

抗原 See all Flotillin 2 (FLOT2) 抗体

Flotillin 2 (FLOT2)
抗原表位
15

4

2

2

2

2

2

1

1

1

1

1
AA 122-379
适用
31

28

16

1

1

1

1

1

1

1

1

1

1

1

1
人, 大鼠, 小鼠, 犬, 小鸡
宿主
39

4

1
小鼠
Compatible Secondaries
克隆类型
43

1
单克隆
标记
23

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Flotillin 2 antibody is un-conjugated
应用范围
22

13

13

11

11

9

5

5

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

交叉反应

犬, 大鼠, 小鼠, 小鸡

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human ESA aa. 122-379

克隆位点

29-Flotillin

亚型

IgG1

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anti-Flotillin 2 (FLOT2) (C-Term) antibody
FLOT2 适用: 人 WB, IHC (p), IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (AA 1-379) antibody
FLOT2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (AA 1-379) antibody
FLOT2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G6 unconjugated

anti-Flotillin 2 (FLOT2) (AA 169-344) antibody
FLOT2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (AA 239-428) antibody
FLOT2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (AA 1-379) antibody
FLOT2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (C-Term) antibody
Verified FLOT2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) antibody
FLOT2 适用: 化学剂 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) antibody
FLOT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Flotillin 2 (FLOT2) (AA 151-250) antibody
FLOT2 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

说明

Related Products: ABIN968536, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
Nebl, Pestonjamasp, Leszyk, Crowley, Oh, Luna: "Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43399-409, (2002) (PubMed).

Salzer, Hinterdorfer, Hunger, Borken, Prohaska: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." in: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).

Rybin, Xu, Lisanti, Steinberg: "Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41447-57, (2001) (PubMed).

Stuermer, Lang, Kirsch, Wiechers, Deininger, Plattner: "Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2." in: Molecular biology of the cell, Vol. 12, Issue 10, pp. 3031-45, (2001) (PubMed).

Schroeder, Stewart-Galetka, Mandavilli, Parry, Goldsmith, Duvic: "Cloning and characterization of a novel epidermal cell surface antigen (ESA)." in: The Journal of biological chemistry, Vol. 269, Issue 31, pp. 19983-91, (1994) (PubMed).
抗原

Flotillin 2 (FLOT2)

别名

Flotillin-2 (FLOT2 产品)

别名

ECS-1 antibody, ECS1 antibody, ESA antibody, ESA1 antibody, M17S1 antibody, AI573412 antibody, Esa antibody, reggie-2 antibody, CG11547 antibody, CG14409 antibody, CG32593 antibody, DmFlo2 antibody, Dmel\\CG32593 antibody, FLO2 antibody, FLO[Dm]-2 antibody, Flo2 antibody, flo2 antibody, reggie-1 antibody, ecs-1 antibody, ecs1 antibody, esa antibody, esa1 antibody, flotillin-2 antibody, FLOT2 antibody, fb48a04 antibody, im:7143869 antibody, wu:fb48a04 antibody, zgc:55821 antibody, flotillin 2 antibody, Flotillin 2 antibody, flotillin 2 L homeolog antibody, flotillin 2a antibody, FLOT2 antibody, Flot2 antibody, Flo2 antibody, flot2.L antibody, flot2 antibody, flot2a antibody

背景

Flotillin-2/ESA (epidermal surface antigen) plays a role in intercellular epidermal adhesion. Epidermal surface proteins have an important role in normal epidermal maintenance and function. In addition, they are involved in various autoimmune diseases in which auto-antibodies bind to normal epidermal cell surface proteins. This binding causes cell disadherence that leads to blister formation. Such antibodies have been utilized to identify new proteins involved in epidermal cell adhesion. One of these antibodies, ECS-1, was used to isolate Flotillin-2/ESA. The single copy ESA gene is located on the long arm of human chromosome 17, in the region containing the gene for neurofibromatosis 1 (NF1). ESA mRNA is expressed in cultured keratinocytes, melanocytes, fibroblasts, and carcinoma and melanoma cell lines. Flotillin-2/ESA may play a critical role in epidermal structure and maintenance.
Synonyms: ESA

分子量

42 kDa