Villin 1 抗体 (AA 1-827)
(5 references)-
- 抗原 See all Villin 1 (VIL1) 抗体
- Villin 1 (VIL1)
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抗原表位
- AA 1-827
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Villin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 人
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Cow Villin aa. 1-827
- 克隆位点
- 12-Villin
- 亚型
- IgG1
- Top Product
- Discover our top product VIL1 Primary Antibody
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anti-Villin 1 (VIL1) (AA 1-320) antibody
VIL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Villin 1 (VIL1) (N-Term) antibodyVIL1 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Villin 1 (VIL1) (AA 1-209) antibodyVIL1 适用: 人 WB, IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3E5G11 unconjugated
anti-Villin 1 (VIL1) (AA 1-209) antibodyVIL1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 5E3B2 unconjugated
anti-Villin 1 (VIL1) (AA 180-207), (N-Term) antibodyVIL1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17824 unconjugated
anti-Villin 1 (VIL1) (AA 1-421) antibodyVIL1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Villin 1 (VIL1) (AA 179-311) antibodyVIL1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VIL1-1314 unconjugated
anti-Villin 1 (VIL1) (AA 1-421) antibodyVIL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Villin 1 (VIL1) (AA 179-311) antibodyVIL1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rVIL1-1325 unconjugated Recombinant Antibody
anti-Villin 1 (VIL1) (AA 600-700) antibodyVIL1 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-459R unconjugated Recombinant Antibody
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- 说明
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Related Products: ABIN968551, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2)." in: European journal of biochemistry / FEBS, Vol. 269, Issue 7, pp. 1866-76, (2002) (PubMed).
: "Tyrosine phosphorylation of villin regulates the organization of the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 276, Issue 39, pp. 36163-7, (2001) (PubMed).
: "Regulation of apical membrane Na+/H+ exchangers NHE2 and NHE3 in intestinal epithelial cell line C2/bbe." in: The American journal of physiology, Vol. 275, Issue 3 Pt 1, pp. C693-701, (1998) (PubMed).
: "An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin." in: Cell, Vol. 70, Issue 1, pp. 81-92, (1992) (PubMed).
: "From the structure to the function of villin, an actin-binding protein of the brush border." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 12, Issue 9, pp. 403-8, (1991) (PubMed).
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: "Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2)." in: European journal of biochemistry / FEBS, Vol. 269, Issue 7, pp. 1866-76, (2002) (PubMed).
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- 抗原
- Villin 1 (VIL1)
- 别名
- Villin (VIL1 产品)
- 别名
- D2S1471 antibody, VIL antibody, Vil antibody, vil1 antibody, MGC64339 antibody, VIL1 antibody, vil1l antibody, zgc:55779 antibody, villin 1 antibody, villin 1 S homeolog antibody, VIL1 antibody, Vil1 antibody, vil1.S antibody, vil1 antibody
- 背景
- The isolated intestinal microvillus cytoskeleton (core) consists of four major proteins: actin, villin, fimbrin, and brush border myosin-I. These proteins can assemble in vitro into structures resembling native microvillus cores. Of these components, villin, and brush border myosin-I show tissue-specific expression, so they may be involved in the morphogenesis of intestinal microvilli. Found in association with the microvillar actin bundles of the intestinal brush border, villin is a 95 kDa protein composed of two very similar domains of approximately 44 kDa each, the core, and a C-terminal domain of 8 kDa, the headpiece. The core has been shown to contain villin's Ca[2+] regulated capping, nucleating, and severing activities, but it cannot induce the formation of microfilament bundles without the headpiece. Villin is a useful differentiation marker of early embryogenesis and may be useful in diagnosis and follow-up of colorectal cancers. It has been demonstrated that villin is necessary for both the cytoskeletal and membrane protein organization of a functional brush border. This antibody is routinely tested by western blot analysis.
- 分子量
- 95 kDa
- 途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
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