STXBP1 抗体 (AA 18-1)
(6 references)-
- 抗原 See all STXBP1 抗体
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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抗原表位
- AA 18-1
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This STXBP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 小鼠, 人
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat Munc-18-1 aa. 381-567
- 克隆位点
- 31-Munc
- 亚型
- IgG1
- Top Product
- Discover our top product STXBP1 Primary Antibody
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anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-168) antibody
STXBP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodyVerified STXBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 295-594) antibodySTXBP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 245-594) antibodySTXBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (C-Term) antibodySTXBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 74-169) antibodySTXBP1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6D1 unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 184-216), (N-Term) antibodySTXBP1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) antibodySTXBP1 适用: 小鼠, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 1 (STXBP1) (AA 1-603) antibodySTXBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Syntaxin 3b is a t-SNARE specific for ribbon synapses of the retina." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 550-9, (2008) (PubMed).
: "Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a." in: Molecular and cellular biology, Vol. 22, Issue 15, pp. 5518-26, (2002) (PubMed).
: "Control of fusion pore dynamics during exocytosis by Munc18." in: Science (New York, N.Y.), Vol. 291, Issue 5505, pp. 875-8, (2001) (PubMed).
: "Munc-18 associates with syntaxin and serves as a negative regulator of exocytosis in the pancreatic beta -cell." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41521-7, (2001) (PubMed).
: "Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 4957-66, (1998) (PubMed).
: "Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin." in: Nature, Vol. 366, Issue 6453, pp. 347-51, (1993) (PubMed).
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: "Syntaxin 3b is a t-SNARE specific for ribbon synapses of the retina." in: The Journal of comparative neurology, Vol. 510, Issue 5, pp. 550-9, (2008) (PubMed).
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- 抗原
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
- 别名
- Munc-18 (STXBP1 产品)
- 别名
- MUNC18-1 antibody, NSEC1 antibody, P67 antibody, RBSEC1 antibody, UNC18 antibody, AI317162 antibody, AI326233 antibody, MMS10-G antibody, Ms10g antibody, Munc-18a antibody, Munc18-1 antibody, N-sec1 antibody, Rb-sec1 antibody, Sxtbp1 antibody, Unc18-1 antibody, Unc18h antibody, nsec1 antibody, fj43h10 antibody, stxbp1 antibody, wu:fj36d12 antibody, wu:fj43h10 antibody, zgc:114171 antibody, rop antibody, unc18 antibody, hunc18 antibody, rbsec1 antibody, munc18-1 antibody, MGC146482 antibody, ANC18HA antibody, NSEC1A antibody, Sec1 antibody, n-sec1 antibody, nSec1 antibody, rbSec1 antibody, rbSec1A antibody, rbSec1B antibody, UNC18A antibody, si:rp71-10d23.3 antibody, syntaxin binding protein 1 antibody, syntaxin binding protein 1a antibody, syntaxin binding protein 1 L homeolog antibody, syntaxin binding protein 1b antibody, STXBP1 antibody, Stxbp1 antibody, stxbp1a antibody, stxbp1 antibody, Tb09.160.0780 antibody, stxbp1.L antibody, stxbp1b antibody
- 背景
- There are two Munc-18 isoforms: Munc-18-1 and Munc-18-2. Munc-18-1 (n-sec1 or rb-sec1, 68 kDa) is a neuronal protein that binds tightly to syntaxin 1 and functions in synaptic vesicle exocytosis. Munc-18-2 exhibits 63% amino acid sequence identity with Munc-18-1. Although Munc-18-2 is expressed in most tissues, Munc-18-1 is primarily expressed in brain. Both forms of Munc-18 bind tightly to syntaxins 1A, 2, and 3, but not to syntaxin 4. Syntaxin 1A is a plasma membrane protein implicated in synaptic vesicle docking. Following calcium entry into the presynaptic nerve terminal, the neurotransmitter-containing synaptic vesicle fuses with the plasma membrane at a region known as the active zone. Thus, by virtue of its interaction with syntaxin 1A, Munc-18-1 is thought to have an essential function in neurotransmitter release.
- 分子量
- 68 kDa
- 途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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