DNM2 抗体 (AA 274-555)
(5 references)-
- 抗原 See all DNM2 抗体
- DNM2 (Dynamin 2 (DNM2))
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抗原表位
- AA 274-555
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DNM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat Dynamin II aa. 274-555
- 克隆位点
- 27-Dynamin II
- 亚型
- IgG2a
- Top Product
- Discover our top product DNM2 Primary Antibody
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anti-Dynamin 2 (DNM2) (AA 533-731) antibody
DNM2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 2 (DNM2) (AA 520-744) antibodyDNM2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3F5F3 unconjugated
anti-Dynamin 2 (DNM2) antibodyDNM2 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Monoclonal 1D8 unconjugated Recombinant Antibody
anti-Dynamin 2 (DNM2) (AA 213-247) antibodyDNM2 适用: 人, 小鼠 WB, IF, FACS 宿主: 兔 Polyclonal RB56171 unconjugated
anti-Dynamin 2 (DNM2) antibodyDNM2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 2 (DNM2) antibodyDNM2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 2 (DNM2) (AA 611-710) antibodyDNM2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C9 unconjugated
anti-Dynamin 2 (DNM2) (AA 640-1119) antibodyDNM2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 2 (DNM2) (AA 607-866) antibodyDNM2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dynamin 2 (DNM2) (AA 61-150) antibodyDNM2 适用: 人, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389, ABIN968535
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
: "Dynamin is required for the activation of mitogen-activated protein (MAP) kinase by MAP kinase kinase." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35301-4, (2000) (PubMed).
: "Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape." in: The Journal of cell biology, Vol. 151, Issue 1, pp. 187-98, (2000) (PubMed).
: "Identification of dynamin 2, an isoform ubiquitously expressed in rat tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 2, pp. 644-8, (1994) (PubMed).
: "Differential expression and regulation of multiple dynamins." in: The Journal of biological chemistry, Vol. 269, Issue 6, pp. 4547-54, (1994) (PubMed).
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: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
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- 抗原
- DNM2 (Dynamin 2 (DNM2))
- 别名
- Dynamin II (DNM2 产品)
- 别名
- dynamin-2 antibody, cmtdi1 antibody, cmtdib antibody, dyn2 antibody, dynII antibody, CMT2M antibody, CMTDI1 antibody, CMTDIB antibody, DI-CMTB antibody, DYN2 antibody, DYNII antibody, LCCS5 antibody, Dyn2 antibody, Udnm antibody, DYIIAAB antibody, dnm2 antibody, zgc:114072 antibody, dynamin 2 antibody, dynamin 2 L homeolog antibody, dynamin 2a antibody, dynamin 2-like antibody, DNM2 antibody, dnm2 antibody, dnm2.L antibody, Dnm2 antibody, dnm2a antibody, DNM2L antibody
- 背景
- Dynamin is a membrane-associated GTPase that binds to GTP, microtubules, and phospholipids. Northern blot analysis has shown dynamin to be present in most tissues but at an amount about 20-fold lower than that in brain. There are at least two distinct dynamin genes in mammals. Transcripts of both dynamin genes are alternatively spliced at two or more sites. The first site is identical in both dynamins, whereas, the second site differs. The two gene products are known as Dynamin I and Dynamin II and show 79% identity. Dynamin I is expressed almost exclusively in the central nervous system while Dynamin II expression is ubiquitous. The two proteins are highly homologous in the N-terminal region, while the C-terminal domain shows significant divergence. The GTPase activity of Dynamin I is stimulated several fold by binding to microtubules, phospholipids, and membranous vesicles. Dynamin I is a good substrate of PKC in vitro as well as in vivo in resting nerve terminals. In vitro, phosphorylation occurs at the C-terminus of Dynamin I and this enhances the GTPase activity more than 10-fold. However, Dynamin II is not a substrate of PKC and its activity does not appear to be affected by phosphorylation. These data suggest that the function of the common N-terminal domain between Dynamin I and II may be differentially specified by distinct C-terminal domains.
- 分子量
- 100 kDa
- 途径
- Toll-Like Receptors Cascades
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