NCK1 抗体 (AA 279-377)
(5 references)-
- 抗原 See all NCK1 抗体
- NCK1 (NCK Adaptor Protein 1 (NCK1))
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抗原表位
- AA 279-377
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适用
- 人, 小鼠, 大鼠, 犬, Cow, Frog, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NCK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 交叉反应
- 牛, 小鸡, 犬, Frog, 小鼠, 大鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human NCK aa. 279-377
- 克隆位点
- 108-NCK
- 亚型
- IgG2b
- Top Product
- Discover our top product NCK1 Primary Antibody
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anti-NCK Adaptor Protein 1 (NCK1) antibody
NCK1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 185-294) antibodyNCK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 猴 WB, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 58-377) antibodyNCK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 53-333) antibodyNCK1 适用: 人 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (Internal Region) antibodyNCK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "EphB receptors interact with NMDA receptors and regulate excitatory synapse formation." in: Cell, Vol. 103, Issue 6, pp. 945-56, (2001) (PubMed).
: "Regulation of Cbl phosphorylation by the Abl tyrosine kinase and the Nck SH2/SH3 adaptor." in: Oncogene, Vol. 20, Issue 30, pp. 4058-69, (2001) (PubMed).
: "Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck." in: The Journal of biological chemistry, Vol. 276, Issue 25, pp. 22003-10, (2001) (PubMed).
: "An oncogenic epidermal growth factor receptor signals via a p21-activated kinase-caldesmon-myosin phosphotyrosine complex." in: The Journal of biological chemistry, Vol. 275, Issue 45, pp. 35328-34, (2000) (PubMed).
: "Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent ..." in: The EMBO journal, Vol. 15, Issue 18, pp. 4940-8, (1996) (PubMed).
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: "EphB receptors interact with NMDA receptors and regulate excitatory synapse formation." in: Cell, Vol. 103, Issue 6, pp. 945-56, (2001) (PubMed).
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- 抗原
- NCK1 (NCK Adaptor Protein 1 (NCK1))
- 别名
- NCK (NCK1 产品)
- 别名
- NCK antibody, NCKalpha antibody, nck-1 antibody, NCK1 antibody, 6330586M15Rik antibody, D230010O13Rik antibody, Nck antibody, Nck-1 antibody, Nck1 antibody, nck antibody, nck1-a antibody, nck1-b antibody, nckalpha antibody, NCK adaptor protein 1 antibody, non-catalytic region of tyrosine kinase adaptor protein 1 antibody, NCK adaptor protein 1b antibody, NCK adaptor protein 1 L homeolog antibody, NCK1 antibody, Nck1 antibody, nck1b antibody, nck1.L antibody
- 背景
- NCK is a 47 kDa protein that belongs to a class of signaling molecules called adaptors. These proteins exert their effects by coupling activated receptors to downstream effectors. NCK is comprised almost entirely of one SH2 and three SH3 domains and it possesses no intrinsic catalytic activity. Investigations of its interactions with cellular proteins have found constitutive association of NCK with various Ser/THr kinases, such as p21-associated kinase (PAK) and casein kinase 1. Other proteins that directly interact with NCK are: Sos, Cbl, Wiskott-Aldrich syndrome protein (WASP), IRS1, and multiple tyrosine kinase receptors. The presence of NCK is necessary for the mitogenic response elicited by PDGF in some cells. In addition, the Drosophila homologue of NCK is involved in regulating cytoskeletal organization. This antibody is routinely tested by western blot analysis.
- 分子量
- 47 kDa
- 途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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