FGF2 抗体 (AA 1-155)
(5 references)-
- 抗原 See all FGF2 抗体
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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抗原表位
- AA 1-155
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FGF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 小鼠, 大鼠, 犬, 小鸡
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human bFGF aa. 1-155
- 克隆位点
- 6-basic FGF
- 亚型
- IgG2a
- Top Product
- Discover our top product FGF2 Primary Antibody
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anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-250) antibody
FGF2 适用: 人, 小鼠, 大鼠, 兔, 绵羊 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 159-288) antibodyFGF2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibodyKO Validated FGF2 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (Middle Region) antibodyFGF2 适用: 人, 小鼠, 大鼠, 兔, 犬, 绵羊, Cow, 斑马鱼, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 26-153) antibodyFGF2 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (C-Term) antibodyFGF2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 189-288) antibodyFGF2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1A9B2 unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibodyFGF2 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 1D6B5 unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) (AA 143-288) antibodyFGF2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 2 (Basic) (FGF2) antibodyFGF2 适用: 人 WB 宿主: 兔 Polyclonal RB52659 unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Antimyeloma efficacy of thalidomide in the SCID-hu model." in: Blood, Vol. 100, Issue 12, pp. 4162-8, (2002) (PubMed).
: "Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors." in: Molecular biology of the cell, Vol. 12, Issue 2, pp. 449-62, (2001) (PubMed).
: "Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability." in: The Journal of biological chemistry, Vol. 271, Issue 10, pp. 5663-70, (1996) (PubMed).
: "Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 271, Issue 21, pp. 12578-84, (1996) (PubMed).
: "Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells." in: The Journal of cell biology, Vol. 127, Issue 1, pp. 203-23, (1994) (PubMed).
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: "Antimyeloma efficacy of thalidomide in the SCID-hu model." in: Blood, Vol. 100, Issue 12, pp. 4162-8, (2002) (PubMed).
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- 抗原
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
- 别名
- basic FGF (FGF2 产品)
- 别名
- BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody
- 背景
- Basic Fibroblast Growth Factor (bFGF) is a family member of the cell-differentiating and growth promoting factors. Basic FGF exists as multiple isoforms ranging from 18-24kDa that are derived from a single mRNA species under unique translational conditions. The 18kDa isoform is primarily cytosolic, but is also secreted and may form reservoirs of bFGF in the extracellular matrix. In contrast, the larger isoforms are predominantly nuclear. At the cellular level, bFGF is a potent mitogen and promotes cell survival by inhibiting apoptosis. At the tissue level, it is involved in wound repair and induces angiogenesis. In addition, bFGF is a significant target in cancer research because it is over-expressed in some cancers and may enhance a tumor's metastatic potential.
- 分子量
- 18-24 kDa
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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