(5 references)-
- 抗原 See all tau 抗体
- tau (tau Protein)
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This tau antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- TAU-5
- 亚型
- IgG1
- Top Product
- Discover our top product tau Primary Antibody
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anti-tau Protein (AA 130-386) antibody
适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 34-368) antibody适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (pSer396) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 677-707) antibody适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 681-758) antibody适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-tau Protein antibody适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 12F4 unconjugated
anti-tau Protein (AA 92-400) antibody适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (pSer202), (pThr205) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-tau Protein (AA 12-24), (pTyr18) antibody适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 小鼠 Monoclonal 9G3 unconjugated
anti-tau Protein antibody适用: 人 WB, ELISA, IF, ICC, DB 宿主: 小鼠 Monoclonal 1D5 unconjugated
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- 说明
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Related Products: ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Rapid dephosphorylation of tau in heat-shocked fetal rat cerebral explants: prevention and hyperphosphorylation by inhibitors of protein phosphatases PP1 and PP2A." in: Journal of neurochemistry, Vol. 65, Issue 1, pp. 396-406, (1995) (PubMed).
: "Differential distribution of tau proteins in developing cat cerebellum." in: Brain research bulletin, Vol. 33, Issue 2, pp. 155-61, (1994) (PubMed).
: "Tau 2: a probe for a Ser conformation in the amino terminus of tau." in: Journal of neurochemistry, Vol. 58, Issue 3, pp. 960-6, (1992) (PubMed).
: "Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties." in: Journal of neuroscience research, Vol. 25, Issue 3, pp. 420-30, (1990) (PubMed).
: "Phosphorylation determines two distinct species of Tau in the central nervous system." in: Cell motility and the cytoskeleton, Vol. 8, Issue 3, pp. 210-26, (1988) (PubMed).
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: "Rapid dephosphorylation of tau in heat-shocked fetal rat cerebral explants: prevention and hyperphosphorylation by inhibitors of protein phosphatases PP1 and PP2A." in: Journal of neurochemistry, Vol. 65, Issue 1, pp. 396-406, (1995) (PubMed).
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- 抗原
- tau (tau Protein)
- 别名
- Tau (tau 产品)
- 背景
- Tau proteins are microtuble-associated proteins (MAPs) that are thought to function by stabilizing microtubles. They comprise a family of multiple polypeptides that originate from one gene. Alternate splicing of Tau mRNA and differential phosphorylation contribute to the heterogeneity of Tau. Typically, Tau proteins migrate between ~ 45-70 kDa with isoelectric points ranging from 6.5-8.0. Tau expression is widespread in the brain and is found in most cell types within the mammalian central nervous system. Tau has a complex biochemical nature that is partly due to its many isoforms. The number and molecular weights of Tau forms changes during brain development. Additionally, the molecular wieghts and forms of Tau proteins at a given point of development vary between species. Antibodies directed against different epitopes have been used to distinguish between Tau forms. The monoclonal antibody TAU-5 recognizes a phosphorylation-independent epitope on Tau proteins. The reduced molecular weight of Tau proteins may range between 45 kDa to 95 kDa. The TAU-5 antibody reacts with a phosphorylation-independent epitope in the middle of tau. It recognizes both the phosphorylated and non-phosphorylated form of Tau. The antibody has been characterized in rat tissue.
- 分子量
- 45-70 kDa
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