Cyclin A 抗体
(6 references)-
- 抗原 See all Cyclin A (CCNA2) 抗体
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cyclin A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)
- 品牌
- BD Pharmingen™
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human Cyclin A Recombinant Protein
- 克隆位点
- BF683
- 亚型
- IgE
- Top Product
- Discover our top product CCNA2 Primary Antibody
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anti-Cyclin A2 (CCNA2) antibody
KO Validated CCNA2 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 105-233) antibodyCCNA2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6B4D11 unconjugated
anti-Cyclin A2 (CCNA2) (AA 190-270) antibodyCCNA2 适用: 人, 小鼠, 大鼠, 猴 WB, IF, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 1-200) antibodyCCNA2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84) antibodyCCNA2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 375-431) antibodyCCNA2 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 适用: 人, 小鼠, Cow, Green Monkey, Mink IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal E67 unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (C-Term) antibodyCCNA2 适用: 人, 小鼠 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 适用: 人 ELISA, IP 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968586, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry." in: Leukemia, Vol. 9, Issue 5, pp. 893-9, (1995) (PubMed).
: "Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1." in: Experimental cell research, Vol. 220, Issue 1, pp. 226-31, (1995) (PubMed).
: "The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2." in: Journal of virology, Vol. 67, Issue 5, pp. 2456-65, (1993) (PubMed).
: "Mammalian G1 cyclins." in: Cell, Vol. 73, Issue 6, pp. 1059-65, (1993) (PubMed).
: "Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F." in: Nature, Vol. 355, Issue 6356, pp. 176-9, (1992) (PubMed).
: "Interaction between human cyclin A and adenovirus E1A-associated p107 protein." in: Science (New York, N.Y.), Vol. 255, Issue 5040, pp. 87-90, (1992) (PubMed).
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: "Expression of cyclins A, D2 and D3 in individual normal mitogen stimulated lymphocytes and in MOLT-4 leukemic cells analyzed by multiparameter flow cytometry." in: Leukemia, Vol. 9, Issue 5, pp. 893-9, (1995) (PubMed).
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- 抗原
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- 别名
- Cyclin A (CCNA2 产品)
- 别名
- CCN1 antibody, CCNA antibody, AA408589 antibody, Ccn-1 antibody, Ccn1 antibody, Ccna antibody, CycA2 antibody, Cyca antibody, cb671 antibody, chunp6924 antibody, wu:fi36f03 antibody, CYCA antibody, Cyclin-A2 antibody, ccna2 antibody, ccn1 antibody, ccna antibody, ccna1 antibody, Cyclin-A antibody, cyclinA antibody, cyclin A2 antibody, cyclin A2 S homeolog antibody, cyclin A2 L homeolog antibody, CCNA2 antibody, Ccna2 antibody, ccna2 antibody, ccna2.S antibody, ccna2.L antibody
- 背景
- Cyclins and cyclin-dependent kinases (cdks) are evolutionarily conserved proteins that are essential for cell-cycle control in eukaryotes. Cyclins (regulatory subunits) bind to cdks (catalytic subunits) to form complexes that regulate the progression of the cell cycle. The main cyclin-cdks complexes formed in vertebrate cells are cyclin D-cdk4 (G0/G1), cyclin E-cdk2 (G1/S), cyclin A-cdk2 (S) and cyclin B1-cdk1 (G2/M). These complexes are regulated by activating and inhibitory phosphorylation events, as well as by interactions with small regulatory proteins including p21 and p27Kip1. Specific substrates for cdk-cyclin complexes include nuclear lamins, histones, oncogenes (e.g., c-abl and SV40 large T-Ag), tumor suppressor genes (e.g., retinoblastoma protein, Rb), nucleolin and others. Cyclin A is involved in both S-phase and G2/M transitions of the cell cycle through its association with cdk2 and cdk1, respectively. Cyclin A may also form a complex with the adenovirus oncoprotein E1A which has DNA binding activity. Human cyclin A has been reported to migrate between 54-60 kDa by SDS-PAGE and clone BF683 reportedly does not cross-react with mouse, rat or mink cyclin A.
- 分子量
- 54-60 kDa
- 途径
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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