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ASPSCR1 抗体

ASPSCR1 适用: 小鼠 ELISA, WB Monoclonal unconjugated
产品编号 ABIN967214
发货至: 中国
  • 抗原 See all ASPSCR1 抗体
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    适用
    • 43
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    小鼠
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    克隆类型
    • 64
    • 6
    单克隆
    标记
    • 32
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    This ASPSCR1 antibody is un-conjugated
    应用范围
    • 51
    • 31
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
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    ELISA, Western Blotting (WB)
    特异性
    Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product ASPSCR1 Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.2%BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

  • 抗原
    ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
    别名
    TUG (ASPSCR1 产品)
    背景
    The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
    基因ID
    68938
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