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- 抗原 See all ASPSCR1 抗体
- ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
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适用
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克隆类型
- 单克隆
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标记
- This ASPSCR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Ni-NTA purified truncated recombinant TUG expressed in E. Coli strain BL21 (DE3)
- 纯化方法
- Antibodies are purified by protein A affinity chromatography
- 亚型
- IgG1
- Top Product
- Discover our top product ASPSCR1 Primary Antibody
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- 应用备注
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Western Blot: 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.2%BSA
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).
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Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).
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- 抗原
- ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))
- 别名
- TUG (ASPSCR1 产品)
- 别名
- tug antibody, aspl antibody, asps antibody, rcc17 antibody, ubxd9 antibody, aspcr1 antibody, ASPCR1 antibody, ASPL antibody, ASPS antibody, RCC17 antibody, TUG antibody, UBXD9 antibody, UBXN9 antibody, 1190006K01Rik antibody, ASPC antibody, ASPSCR1, UBX domain containing tether for SLC2A4 antibody, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antibody, alveolar soft part sarcoma chromosome region, candidate 1 antibody, alveolar soft part sarcoma chromosome region, candidate 1 (human) antibody, ASPSCR1 antibody, aspscr1.S antibody, Aspscr1 antibody, aspscr1 antibody, Bm1_55980 antibody
- 背景
- The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominantnegative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.
- 基因ID
- 68938
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