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TRIM25 抗体 (N-Term)

This anti-TRIM25 antibody is a 兔 多克隆 antibody detecting TRIM25 in IHC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN967204
发货至: 中国

Quick Overview for TRIM25 抗体 (N-Term) (ABIN967204)

抗原

See all TRIM25 抗体
TRIM25 (Tripartite Motif Containing 25 (TRIM25))

适用

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宿主

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克隆类型

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  • 9
多克隆

标记

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This TRIM25 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM25 (Tripartite motif-containing protein 25)
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Inoue, Orimo, Hosoi, Kondo, Toyoshima, Kondo, Ikegami, Ouchi, Orimo, Muramatsu: "Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).

  • 抗原

    TRIM25 (Tripartite Motif Containing 25 (TRIM25))

    别名

    TRIM25

    背景

    TRIM25 (Tripartite motif-containing protein 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of TRIM25 is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary TRIM25 contains 1 B30.2/SPRY domain and 1 RING-type zinc finger.
    Synonyms: EFP (Estrogen-responsive finger protein), RNF147 (RING finger protein 147), ZNF147 (Zinc finger protein 147)
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