TRIM25 抗体 (N-Term)
Quick Overview for TRIM25 抗体 (N-Term) (ABIN967204)
抗原
See all TRIM25 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human TRIM25 (Tripartite motif-containing protein 25)
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限制
- 仅限研究用
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储存条件
- 4 °C
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Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).
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Genomic binding-site cloning reveals an estrogen-responsive gene that encodes a RING finger protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 23, pp. 11117-21, (1994) (PubMed).
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- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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别名
- TRIM25
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背景
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TRIM25 (Tripartite motif-containing protein 25) is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a Bbox type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of TRIM25 is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary TRIM25 contains 1 B30.2/SPRY domain and 1 RING-type zinc finger.
Synonyms: EFP (Estrogen-responsive finger protein), RNF147 (RING finger protein 147), ZNF147 (Zinc finger protein 147)
抗原
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