(3 references)-
- 抗原 See all SRA1 抗体
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
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适用
- 人
- 宿主
- 请咨询
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克隆类型
- 单克隆
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标记
- This SRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Ni-NTA purified truncated recombinant SRA expressed in E. Coli strain BL21 (DE3)
- 纯化方法
- Crude ascites.
- 亚型
- IgG1
- Top Product
- Discover our top product SRA1 Primary Antibody
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anti-Steroid Receptor RNA Activator 1 (SRA1) antibody
SRA1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 1D4H8 unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 92-141) antibodySRA1 适用: 人, 大鼠, Cow, 豚鼠, 马, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 519-556) antibodySRA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal 30A4 unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (truncated) antibodySRA1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1D4H8 unconjugated
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- 应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存条件
- -20 °C
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: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).
: "The steroid receptor RNA activator is the first functional RNA encoding a protein." in: FEBS letters, Vol. 566, Issue 1-3, pp. 43-7, (2004) (PubMed).
: "Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7163-76, (2003) (PubMed).
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: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).
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- 抗原
- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
- 别名
- SRA (SRA1 产品)
- 别名
- SRA antibody, SRAP antibody, STRAA1 antibody, pp7684 antibody, AA959952 antibody, Sra antibody, Srap antibody, Straa1 antibody, Strra1 antibody, zgc:86613 antibody, steroid receptor RNA activator 1 antibody, steroid receptor RNA activator 1 S homeolog antibody, cytoplasmic FMR1 interacting protein 1 antibody, SRA1 antibody, Sra1 antibody, sra1 antibody, sra1.S antibody, CYFIP1 antibody
- 背景
- Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
- 基因ID
- 10011
- 途径
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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