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RAD51 抗体 (Isoform 2)

This anti-RAD51 antibody is a 兔 多克隆 antibody detecting RAD51 in IHC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN966939
发货至: 中国

Quick Overview for RAD51 抗体 (Isoform 2) (ABIN966939)

抗原

See all RAD51 抗体
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

适用

  • 165
  • 75
  • 38
  • 4
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  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 106
  • 62
  • 1

克隆类型

  • 97
  • 72
多克隆

标记

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  • 9
  • 4
  • 4
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  • 4
  • 4
  • 4
  • 4
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  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This RAD51 antibody is un-conjugated

应用范围

  • 117
  • 41
  • 40
  • 37
  • 29
  • 29
  • 22
  • 21
  • 11
  • 11
  • 10
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 抗原表位

    • 48
    • 23
    • 15
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform 2

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human RAD51 homolog protein isoform 2
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Liang, Caporaso, McMaster, Ng, Landgren, Yeager, Chanock, Goldin: "Common genetic variants in candidate genes and risk of familial lymphoid malignancies." in: British journal of haematology, Vol. 146, Issue 4, pp. 418-23, (2009) (PubMed).

    Rebbeck, Mitra, Domchek, Wan, Chuai, Friebel, Panossian, Spurdle, Chenevix-Trench, , Singer, Pfeiler, Neuhausen, Lynch, Garber, Weitzel, Isaacs, Couch, Narod, Rubinstein, Tomlinson, Ganz, Olopade, Tung, Blum, Greenberg, Nathanson, Daly: "Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers." in: Cancer research, Vol. 69, Issue 14, pp. 5801-10, (2009) (PubMed).

    Kovalenko, Plug, Haaf, Gonda, Ashley, Ward, Radding, Golub: "Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 7, pp. 2958-63, (1996) (PubMed).

    Benson, Stasiak, West: "Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA." in: The EMBO journal, Vol. 13, Issue 23, pp. 5764-71, (1995) (PubMed).

  • 抗原

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    别名

    RAD51 homolog protein

    背景

    RAD51 homolog protein isoform 2 is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. RAD51 homolog protein isoform 2 is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Product

    途径

    DNA Damage Repair
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