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- 抗原 See all N-Cadherin (CDH2) 抗体
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This N-Cadherin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
- Rabbit IgG polyclonal antibody for Cadherin-2 (CDH2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human N-Cadherin, identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.
- 亚型
- IgG
- Top Product
- Discover our top product CDH2 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
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Cadherin regulates dendritic spine morphogenesis." in: Neuron, Vol. 35, Issue 1, pp. 77-89, (2002) (PubMed).
: "Genomic structure and chromosomal mapping of the mouse N-cadherin gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8443-7, (1992) (PubMed).
: "N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene." in: Journal of neurochemistry, Vol. 55, Issue 3, pp. 805-12, (1990) (PubMed).
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Cadherin regulates dendritic spine morphogenesis." in: Neuron, Vol. 35, Issue 1, pp. 77-89, (2002) (PubMed).
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- 抗原
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- 别名
- Cadherin-2 (CDH2 产品)
- 别名
- CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody
- 背景
- N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96 % identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11. 2. Cadherin regulates dendritic spine morphogenesis.
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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