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- 抗原 See all MEK1 (MAP2K1) 抗体
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEK1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 特异性
- MEK1 (Ab-221) antibody detects endogenous levels of total MEK1 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human MEK1 around the phosphorylation site of serine 221 (A-N-SP-F-V).
- Top Product
- Discover our top product MAP2K1 Primary Antibody
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- 应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100ug/100ul.
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia." in: Cancer research, Vol. 66, Issue 7, pp. 3401-8, (2006) (PubMed).
: "Phosphorylation of threonine 290 in the activation loop of Tpl2/Cot is necessary but not sufficient for kinase activity." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52117-23, (2004) (PubMed).
: "Negative regulation of MAPKK by phosphorylation of a conserved serine residue equivalent to Ser212 of MEK1." in: The Journal of biological chemistry, Vol. 278, Issue 10, pp. 8118-25, (2003) (PubMed).
: "MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells." in: Oncogene, Vol. 22, Issue 1, pp. 109-16, (2003) (PubMed).
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Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia." in: Cancer research, Vol. 66, Issue 7, pp. 3401-8, (2006) (PubMed).
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- 抗原
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- 别名
- MEK1 (MAP2K1 产品)
- 别名
- Mek1 antibody, CFC3 antibody, MAPKK1 antibody, MEK1 antibody, MKK1 antibody, PRKMK1 antibody, MEKK1 antibody, Prkmk1 antibody, mek-2 antibody, si:ch211-242m18.2 antibody, wu:fj56a12 antibody, wu:fj61b01 antibody, zgc:56557 antibody, ATMEK1 antibody, F20B18.180 antibody, F20B18_180 antibody, MAP kinase/ ERK kinase 1 antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE antibody, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antibody, NMAPKK antibody, MEK antibody, mitogen activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 antibody, mitogen-activated protein kinase kinase 1 L homeolog antibody, MAP kinase/ ERK kinase 1 antibody, Map2k1 antibody, MAP2K1 antibody, map2k1.L antibody, map2k1 antibody, MEK1 antibody
- 途径
- MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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