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MAPK7 抗体 (C-Term, Isoform 1)

MAPK7 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966526
发货至: 中国
  • 抗原 See all MAPK7 抗体
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    抗原表位
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 10
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, Isoform 1
    适用
    • 92
    • 62
    • 57
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 120
    • 4
    • 2
    • 1
    克隆类型
    • 115
    • 12
    多克隆
    标记
    • 38
    • 10
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This MAPK7 antibody is un-conjugated
    应用范围
    • 68
    • 54
    • 53
    • 36
    • 23
    • 18
    • 17
    • 13
    • 7
    • 5
    • 3
    • 1
    • 1
    Immunohistochemistry (IHC)
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human MAPK7 (mitogen-activated protein kinase 7 isoform 1)
    Top Product
    Discover our top product MAPK7 Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C
  • Sawhney, Liu, Brattain: "A novel role of ERK5 in integrin-mediated cell adhesion and motility in cancer cells via Fak signaling." in: Journal of cellular physiology, Vol. 219, Issue 1, pp. 152-61, (2009) (PubMed).

    Zhao, Geng, Ge, Wang, Zhang, Kang: "Activation of ERK5 in angiotensin II-induced hypertrophy of human aortic smooth muscle cells." in: Molecular and cellular biochemistry, Vol. 322, Issue 1-2, pp. 171-8, (2009) (PubMed).

    Montero, Ocaña, Abad, Ortiz-Ruiz, Pandiella, Esparís-Ogando: "Expression of Erk5 in early stage breast cancer and association with disease free survival identifies this kinase as a potential therapeutic target." in: PLoS ONE, Vol. 4, Issue 5, pp. e5565, (2009) (PubMed).

    Zen, Yasui, Nakajima, Zen, Zen, Gen, Mitsuyoshi, Minami, Mitsufuji, Tanaka, Itoh, Nakanuma, Taniwaki, Arii, Okanoue, Yoshikawa: "ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry." in: Genes, chromosomes & cancer, Vol. 48, Issue 2, pp. 109-20, (2008) (PubMed).

    Arnoux, Nassour, LHelgoualch, Hipskind, Savagner: "Erk5 controls Slug expression and keratinocyte activation during wound healing." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4738-49, (2008) (PubMed).

    Buschbeck, Eickhoff, Sommer, Ullrich: "Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29503-9, (2002) (PubMed).

    Esparís-Ogando, Díaz-Rodríguez, Montero, Yuste, Crespo, Pandiella: "Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2." in: Molecular and cellular biology, Vol. 22, Issue 1, pp. 270-85, (2001) (PubMed).

    Purandare, Lee, Patel: "Assignment of big MAP kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids." in: Cytogenetics and cell genetics, Vol. 83, Issue 3-4, pp. 258-9, (1999) (PubMed).

    Kato, Tapping, Huang, Watson, Ulevitch, Lee: "Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor." in: Nature, Vol. 395, Issue 6703, pp. 713-6, (1998) (PubMed).

    English, Pearson, Baer, Cobb: "Identification of substrates and regulators of the mitogen-activated protein kinase ERK5 using chimeric protein kinases." in: The Journal of biological chemistry, Vol. 273, Issue 7, pp. 3854-60, (1998) (PubMed).

  • 抗原
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    别名
    MAPK7 (MAPK7 产品)
    别名
    BMK1 antibody, ERK4 antibody, ERK5 antibody, PRKM7 antibody, Erk5-T antibody, ATMPK7 antibody, F8D23.5 antibody, F8D23_5 antibody, MAP kinase 7 antibody, Bmk1 antibody, Erk5 antibody, Prkm7 antibody, ERK-5 antibody, bmk1 antibody, erk4 antibody, mapk7 antibody, prkm7 antibody, mitogen-activated protein kinase 7 antibody, MAP kinase 7 antibody, mitogen-activated protein kinase 7 L homeolog antibody, MAPK7 antibody, Mapk7 antibody, MPK7 antibody, mapk7.L antibody
    背景
    MAPK7 (mitogen-activated protein kinase 7 isoform 1) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
    Synonyms: BMK1, ERK4, ERK5, PRKM7
    途径
    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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