(3 references)-
- 抗原 See all L3MBTL1 抗体
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This L3MBTL1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human L3MBTL(Lethal(3)malignant brain tumor-like protein )
- Top Product
- Discover our top product L3MBTL1 Primary Antibody
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anti-L(3)mbt-Like 1 (L3MBTL1) (Center) antibody
L3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 1-772) antibodyL3MBTL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 82-298) antibodyL3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 513-752) antibodyL3MBTL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 451-485) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 442-491) antibodyL3MBTL1 适用: 人, 小鼠, 犬, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 221-270) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (N-Term) antibodyL3MBTL1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 144-193) antibodyL3MBTL1 适用: 人, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 15412-20, (2003) (PubMed).
: "Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets." in: Structure (London, England : 1993), Vol. 11, Issue 7, pp. 775-89, (2003) (PubMed).
: "A human homolog of Drosophila lethal(3)malignant brain tumor (l(3)mbt) protein associates with condensed mitotic chromosomes." in: Oncogene, Vol. 18, Issue 26, pp. 3799-809, (1999) (PubMed).
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: "The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)." in: The Journal of biological chemistry, Vol. 278, Issue 17, pp. 15412-20, (2003) (PubMed).
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- 抗原
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
- 别名
- L3MBTL (L3MBTL1 产品)
- 别名
- C630004G01 antibody, L3mbtl antibody, mKIAA0681 antibody, H-L(3)MBT antibody, L3MBTL antibody, ZC2HC3 antibody, dJ138B7.3 antibody, RGD1307316 antibody, l(3)mbt-like (Drosophila) antibody, L3MBTL1, histone methyl-lysine binding protein antibody, l(3)mbt-like 1 (Drosophila) antibody, L3mbtl1 antibody, L3MBTL1 antibody
- 背景
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L3MBTL(Lethal(3)malignant brain tumor-like protein ) is polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. L3MBTL participates in the ETV6-mediated repression. L3MBTL probably plays a role in cell proliferation. Overexpression induces multinucleated cells, suggesting that it is required to accomplish normal mitosis. L3MBTL interacts with ETV6 and is widely expressed. Expression is reduced in colorectal cancer cell line SW480 and promyelocytic leukemia cell line HL-60. In interphase cells, it is scattered throughout the nucleoplasm. In mitotic cells, it strongly associates with condensed chromosomes from the prophase to telophase.
Synonyms: KIAA0681, L3MBT, L3MBTL1 - 途径
- Chromatin Binding
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