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HSD11B1 抗体 (AA 131-145)

HSD11B1 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) Polyclonal unconjugated
产品编号 ABIN966304
发货至: 中国
  • 抗原 See all HSD11B1 抗体
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    抗原表位
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    AA 131-145
    适用
    • 47
    • 24
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
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    克隆类型
    • 40
    • 11
    多克隆
    标记
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This HSD11B1 antibody is un-conjugated
    应用范围
    • 28
    • 15
    • 14
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    免疫原
    A synthetic peptide corresponding to a sequence at the middle region of human HSD11B1 (131-145 aa), different from the mouse sequence by two amino acids.
    Top Product
    Discover our top product HSD11B1 Primary Antibody
  • 限制
    仅限研究用
  • 溶解方式
    0.2ml of distilled water will yield a concentration of 500µg/ml.
    缓冲液
    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
    储存液
    Thimerosal (Merthiolate), Sodium azide
    储存条件
    -20 °C
  • 抗原
    HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
    别名
    HSD11B1 (HSD11B1 产品)
    别名
    11-DH antibody, 11-beta-HSD1 antibody, CORTRD2 antibody, HDL antibody, HSD11 antibody, HSD11B antibody, HSD11L antibody, SDR26C1 antibody, hsd11 antibody, hsd11b antibody, LRRGT00065 antibody, hydroxysteroid 11-beta dehydrogenase 1 antibody, hydroxysteroid (11-beta) dehydrogenase 1b antibody, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antibody, HSD11B1 antibody, HSD11B1b antibody, hsd11b1.L antibody, Hsd11b1 antibody
    背景
    11-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system.In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors.It is inhibited by carbenoxolone, a drug typically used in the treatment of peptic ulcersTannin et al. (1991) localized the HSD11B1 gene to chromosome 1. The localization was confirmed by isolating the gene from a chromosome 1-specific library using the cDNA as a probe. Schutte et al. (2000) mapped the HSD11B1 gene to 1q32-q41.
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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