(7 references)-
- 抗原 See all MLL/KMT2A (MLL) 抗体
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MLL/KMT2A antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to near N-terminal residues of human HRX (Histone-lysine N-methyltransferase HRX)
- Top Product
- Discover our top product MLL Primary Antibody
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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3850-3900) antibody
MLL 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3751-3968) antibodyMLL 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 10F8D7 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 801-956) antibodyMLL 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4A5A12 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 2829-2883) antibodyMLL 适用: 人, 小鼠 WB, ChIP, ICC, ChIP-seq, IF 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3561-3670) antibodyMLL 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (AA 3879-3908), (C-Term) antibodyMLL 适用: 人 IHC (p), FACS 宿主: 兔 Polyclonal RB02951 unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) antibodyMLL 适用: 人 IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL) (C-Term) antibodyMLL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias." in: British journal of haematology, Vol. 93, Issue 4, pp. 966-72, (1996) (PubMed).
: "The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing." in: DNA and cell biology, Vol. 14, Issue 6, pp. 475-83, (1995) (PubMed).
: "Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia." in: Cancer research, Vol. 54, Issue 9, pp. 2327-30, (1994) (PubMed).
: "Two distinct portions of LTG19/ENL at 19p13 are involved in t(11;19) leukemia." in: Oncogene, Vol. 8, Issue 10, pp. 2617-25, (1993) (PubMed).
: "Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias." in: Cell, Vol. 71, Issue 4, pp. 691-700, (1992) (PubMed).
: "The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene." in: Cell, Vol. 71, Issue 4, pp. 701-8, (1992) (PubMed).
: "Cloning a replication function from the streptomycete bacteriophage FP43." in: Gene, Vol. 113, Issue 1, pp. 113-7, (1992) (PubMed).
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: "Exon/intron structure of the human ALL-1 (MLL) gene involved in translocations to chromosomal region 11q23 and acute leukaemias." in: British journal of haematology, Vol. 93, Issue 4, pp. 966-72, (1996) (PubMed).
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- 抗原
- MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))
- 别名
- HRX (MLL 产品)
- 别名
- ALL-1 antibody, CXXC7 antibody, HRX antibody, HTRX1 antibody, MLL antibody, MLL/GAS7 antibody, MLL1A antibody, TET1-MLL antibody, TRX1 antibody, WDSTS antibody, 6430520K01 antibody, All1 antibody, Cxxc7 antibody, Mll antibody, Mll1 antibody, mKIAA4050 antibody, lysine methyltransferase 2A antibody, lysine (K)-specific methyltransferase 2A antibody, KMT2A antibody, Kmt2a antibody
- 背景
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HRX (Histone-lysine N-methyltransferase HRX) functions as histone methyltransferase. HRX methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. HRX promotes PPP1R15A-induced apoptosis. HRX interacts with SBF1 and PPP1R15A. HRX is a component of the MLL complex, at least composed of MLL, ASH2L, RBBP5, DPY30, WDR5, MEN1,HCFC1 and HCFC2. Chromosomal aberrations involving MLL are a cause of acute leukemias. A chromosomal aberration involving MLL may be a cause of chronic neutrophilic leukemia. HRX belongs to the histone-lysine methyltransferase family and TRX/MLL subfamily.
Synonyms: ALL1, CXXC7(CXXC-type zinc finger protein 7), HTRX, KMT2A, TRX1, MLL, Zinc finger protein HRX, Trithorax-like protein, Lysine N-methyltransferase 2A - 途径
- Warburg Effect
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