(4 references)-
- 抗原 See all FANCD2 抗体
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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抗原表位
- Isoform B
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FANCD2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human FANCD2 (Fanconi anemia complementation group D2 isoform b)
- Top Product
- Discover our top product FANCD2 Primary Antibody
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anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibody
FANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-230) antibodyFANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-291) antibodyFANCD2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 893-927) antibodyFANCD2 适用: 人 WB 宿主: 兔 Polyclonal RB49367 unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (Ser371) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array." in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009) (PubMed).
: "Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M." in: Blood, Vol. 114, Issue 1, pp. 174-80, (2009) (PubMed).
: "FANCD2-deficient human fibroblasts are hypersensitive to ionising radiation at oxygen concentrations of 0% and 3% but not under normoxic conditions." in: International journal of radiation biology, Vol. 85, Issue 6, pp. 523-31, (2009) (PubMed).
: "Replication stress induces sister-chromatid bridging at fragile site loci in mitosis." in: Nature cell biology, Vol. 11, Issue 6, pp. 753-60, (2009) (PubMed).
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: "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array." in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009) (PubMed).
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- 抗原
- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
- 别名
- FANCD2 (FANCD2 产品)
- 背景
- The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homologydirected DNA repair. Alternative splicing results in two transcript variants encoding different isoforms.
- 途径
- DNA Damage Repair
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