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- 抗原 See all Factor VIII (F8) 抗体
- Factor VIII (F8) (Coagulation Factor VIII (F8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Factor VIII antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of F8 expressed in E. Coli.
- 克隆位点
- 5E9B2
- 亚型
- IgG1
- Top Product
- Discover our top product F8 Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism." in: Thrombosis and haemostasis, Vol. 98, Issue 5, pp. 1031-9, (2007) (PubMed).
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Elevated factor VIII in hereditary haemorrhagic telangiectasia (HHT): association with venous thromboembolism." in: Thrombosis and haemostasis, Vol. 98, Issue 5, pp. 1031-9, (2007) (PubMed).
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- 抗原
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- 别名
- F8 (F8 产品)
- 别名
- fb61d02 antibody, wu:fb61d02 antibody, Cf-8 antibody, Cf8 antibody, FVIII antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, HEMA antibody, coagulation factor VIIi antibody, coagulation factor VIII antibody, coagulation factor VIII, procoagulant component antibody, f7i antibody, F8 antibody
- 背景
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F8: coagulation factor VIII, procoagulant component. This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Synonyms: AHF, F8B, F8C, HEMA, FVIII - 基因ID
- 2157
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