This Estrogen Receptor alpha antibody is un-conjugated
应用范围
Immunohistochemistry (IHC)
特异性
Estrogen Receptor- (Ab-167) antibody detects endogenous levels of total Estrogen Receptor- protein.
纯化方法
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
免疫原
The antiserum was produced against synthesized non-phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine167 (L-A-SP-T-N).
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
Shah, Rowan: "The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity." in: Molecular endocrinology (Baltimore, Md.), Vol. 19, Issue 3, pp. 732-48, (2005) (PubMed).
Campbell, Bhat-Nakshatri, Patel, Constantinidou, Ali, Nakshatri: "Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance." in: The Journal of biological chemistry, Vol. 276, Issue 13, pp. 9817-24, (2001) (PubMed).