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Cytokeratin 5 抗体

KRT5 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 1E1 unconjugated
产品编号 ABIN965962
发货至: 中国
  • 抗原 See all Cytokeratin 5 (KRT5) 抗体
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    适用
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    宿主
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    小鼠
    克隆类型
    • 83
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    单克隆
    标记
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    This Cytokeratin 5 antibody is un-conjugated
    应用范围
    • 87
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of Cytokeratin 5 expressed in E. Coli.
    克隆位点
    1E1
    亚型
    IgG1
    Top Product
    Discover our top product KRT5 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Gu, Kim, Ichiki, Park, Nagai, Kitajima: "A usual frameshift and delayed termination codon mutation in keratin 5 causes a novel type of epidermolysis bullosa simplex with migratory circinate erythema." in: The Journal of investigative dermatology, Vol. 121, Issue 3, pp. 482-5, (2003) (PubMed).

  • 抗原
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    别名
    Cytokeratin 5 (KRT5 产品)
    别名
    3300001P10Rik antibody, AW146334 antibody, CK5 antibody, K5 antibody, Krt2-5 antibody, Tfip8 antibody, DDD antibody, DDD1 antibody, EBS2 antibody, KRT5A antibody, Sak57 antibody, ckii antibody, wu:fb02h09 antibody, wu:fj02d02 antibody, wu:fk78b12 antibody, zfCKII antibody, KRT75 antibody, CK-5 antibody, Keratin-5 antibody, keratin 5 antibody, Krt5 antibody, KRT5 antibody, krt5 antibody
    背景
    Cytokeratin 5, also known as CK5, KRT5. It is a member of the keratin gene family. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Cytokeratin 5 is expressed in normal basal cells. Mutations of the Cytokeratin5 gene (KRT5) have been shown to result in the autosomal dominant disorderepidermolysis bullosa (EB). Defects in KRT5 are a cause of epidermolysis bullosa simplex.
    Synonyms: K5, CK5, KRT5A, KRT5
    分子量
    62.3kDa
    基因ID
    3852
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