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- 抗原 See all CHEK1 抗体
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHEK1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 特异性
- Chk1 (Ab-317) antibody detects endogenous levels of total Chk1 protein.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human Chk1 around the phosphorylation site of serine 317 (S-S-SP-Q-P)
- Top Product
- Discover our top product CHEK1 Primary Antibody
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- 应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100ug/100ul.
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway." in: Molecular cell, Vol. 19, Issue 5, pp. 607-18, (2005) (PubMed).
: "Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor." in: The EMBO journal, Vol. 24, Issue 6, pp. 1157-69, (2005) (PubMed).
: "DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system." in: The Biochemical journal, Vol. 388, Issue Pt 2, pp. 705-12, (2005) (PubMed).
: "DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains." in: Molecular and cellular biology, Vol. 24, Issue 21, pp. 9478-86, (2004) (PubMed).
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Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway." in: Molecular cell, Vol. 19, Issue 5, pp. 607-18, (2005) (PubMed).
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- 抗原
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- 别名
- CHK1 (CHEK1 产品)
- 别名
- An08g10320 antibody, AO090003000441 antibody, CHK1 antibody, chk1 antibody, C85740 antibody, Chk1 antibody, rad27 antibody, id:ibd2720 antibody, zgc:56093 antibody, CHEK1 antibody, checkpoint kinase 1 antibody, serine/threonine-protein kinase chk1 antibody, serine/threonine-protein kinase Chk1 antibody, CAMK/CAMKL/CHK1 protein kinase Chk1 antibody, checkpoint kinase 1 S homeolog antibody, CHEK1 antibody, ANI_1_2436074 antibody, AOR_1_768154 antibody, PTRG_04183 antibody, SJAG_01680 antibody, PAAG_04978 antibody, MCYG_03290 antibody, VDBG_03742 antibody, chek1.S antibody, Chek1 antibody, chek1 antibody
- 途径
- p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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