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- 抗原 See all MME 抗体
- MME (Membrane Metallo-Endopeptidase (MME))
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适用
- 人
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克隆类型
- 单克隆
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标记
- This MME antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA
- 特异性
- Ni-NTA purified recombinant human CD-10 expressed in E. Coli strain BL21 (DE3).
- 纯化方法
- Antibodies are purified by protein G affinity chromatography.
- 亚型
- IgG2b
- Top Product
- Discover our top product MME Primary Antibody
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- 应用备注
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IHC(P): Dilution 1: 100- 1: 200
IHC(F): Dilution 1: 200- 1: 400
ELISA: Propose dilution 1: 10000.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 储存条件
- -20 °C
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Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." in: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).
: "Expression of granulocyte colony-stimulating factor receptor on CD10-positive human B-cell precursors." in: British journal of haematology, Vol. 89, Issue 3, pp. 623-6, (1995) (PubMed).
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Expression of CD10/neutral endopeptidase in normal and malignant tissues of the human stomach and colon." in: Journal of gastroenterology, Vol. 31, Issue 1, pp. 12-7, (1996) (PubMed).
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- CD10 (MME 产品)
- 别名
- CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody
- 物质类
- Chemical
- 背景
- CD10 is a 100kDa glycoprotein, also designated Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.
- 基因ID
- 4311
- 途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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