SRRT 抗体 (C-Term)
Quick Overview for SRRT 抗体 (C-Term) (ABIN965596)
抗原
See all SRRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ARS2 (Arsenite-resistance protein 2)
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anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 1-796) antibody
SRRT 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (C-Term) antibodyVerified SRRT 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 627-876) antibodySRRT 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 733-766) antibodySRRT 适用: 人, 斑马鱼 WB 宿主: 兔 Polyclonal RB53167 unconjugated
anti-Serrate RNA Effector Molecule Homolog (SRRT) (AA 878-910) antibodySRRT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53166 unconjugated
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- SRRT (Serrate RNA Effector Molecule Homolog (SRRT))
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别名
- ARS2
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背景
- ARS2(Arsenite-resistance protein 2) confers arsenite resistance The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite-resistance protein 1) and ASR2(Arsenite-resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitinlike region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin-dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite.
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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